Difference between revisions of "YER159C"

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'''Description of YER159C:''' Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha<ref name='S000078394'>Cang Y and Prelich G (2002) Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP). Proc Natl Acad Sci U S A 99(20):12727-32 {{SGDpaper|S000078394}} PMID 12237409</ref><ref name='S000073385'>Estruch F and Cole CN (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14(4):1664-76 {{SGDpaper|S000073385}} PMID 12686617</ref><ref name='S000057997'>Goppelt A and Meisterernst M (1996) Characterization of the basal inhibitor of class II transcription NC2 from Saccharomyces cerevisiae. Nucleic Acids Res 24(22):4450-5 {{SGDpaper|S000057997}} PMID 8948634</ref><ref name='S000048426'>Kim S, et al. (1997) The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo. Proc Natl Acad Sci U S A 94(3):820-5
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'''Description of YER159C:''' Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha<ref name='S000048426'>Kim S, et al. (1997) The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo. Proc Natl Acad Sci U S A 94(3):820-5 {{SGDpaper|S000048426}} PMID 9023340</ref><ref name='S000057997'>Goppelt A and Meisterernst M (1996) Characterization of the basal inhibitor of class II transcription NC2 from Saccharomyces cerevisiae. Nucleic Acids Res 24(22):4450-5 {{SGDpaper|S000057997}} PMID 8948634</ref><ref name='S000073385'>Estruch F and Cole CN (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14(4):1664-76 {{SGDpaper|S000073385}} PMID 12686617</ref><ref name='S000078394'>Cang Y and Prelich G (2002) Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP). Proc Natl Acad Sci U S A 99(20):12727-32
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  {{SGDpaper|S000078394}} PMID 12237409</ref>
 
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Revision as of 03:40, 18 December 2008

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Systematic name YER159C
Gene name BUR6
Aliases NCB1
Feature type ORF, Verified
Coordinates Chr V:491953..491525
Primary SGDID S000000961


Description of YER159C: Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha[1][2][3][4]




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References

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  1. Kim S, et al. (1997) The Dr1/DRAP1 heterodimer is a global repressor of transcription in vivo. Proc Natl Acad Sci U S A 94(3):820-5 SGD PMID 9023340
  2. Goppelt A and Meisterernst M (1996) Characterization of the basal inhibitor of class II transcription NC2 from Saccharomyces cerevisiae. Nucleic Acids Res 24(22):4450-5 SGD PMID 8948634
  3. Estruch F and Cole CN (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14(4):1664-76 SGD PMID 12686617
  4. Cang Y and Prelich G (2002) Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP). Proc Natl Acad Sci U S A 99(20):12727-32 SGD PMID 12237409

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