Difference between revisions of "YEL056W"
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| − | '''Description of YEL056W:''' Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing<ref name=' | + | '''Description of YEL056W:''' Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing<ref name='S000043287'>Ruiz-Garcia AB, et al. (1998) HAT1 and HAT2 proteins are components of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4. J Biol Chem 273(20):12599-605 {{SGDpaper|S000043287}} PMID 9575221</ref><ref name='S000049470'>Parthun MR, et al. (1996) The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism. Cell 87(1):85-94 {{SGDpaper|S000049470}} PMID 8858151</ref><ref name='S000053627'>Kelly TJ, et al. (2000) Type B histone acetyltransferase Hat1p participates in telomeric silencing. Mol Cell Biol 20(19):7051-8 |
| − | {{SGDpaper| | + | {{SGDpaper|S000053627}} PMID 10982821</ref> |
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Revision as of 03:40, 18 December 2008
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| Systematic name | YEL056W |
| Gene name | HAT2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:47168..48373 |
| Primary SGDID | S000000782 |
Description of YEL056W: Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing[1][2][3]
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References
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- ↑ Ruiz-Garcia AB, et al. (1998) HAT1 and HAT2 proteins are components of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4. J Biol Chem 273(20):12599-605 SGD PMID 9575221
- ↑ Parthun MR, et al. (1996) The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism. Cell 87(1):85-94 SGD PMID 8858151
- ↑ Kelly TJ, et al. (2000) Type B histone acetyltransferase Hat1p participates in telomeric silencing. Mol Cell Biol 20(19):7051-8 SGD PMID 10982821
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