Difference between revisions of "YBL039C"
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| − | '''Description of YBL039C:''' Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis<ref name=' | + | '''Description of YBL039C:''' Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis<ref name='S000041184'>Yang WL, et al. (1994) Purification and characterization of CTP synthetase, the product of the URA7 gene in Saccharomyces cerevisiae. Biochemistry 33(35):10785-93 {{SGDpaper|S000041184}} PMID 8075080</ref><ref name='S000042459'>Ozier-Kalogeropoulos O, et al. (1994) Use of synthetic lethal mutants to clone and characterize a novel CTP synthetase gene in Saccharomyces cerevisiae. Mol Gen Genet 242(4):431-9 {{SGDpaper|S000042459}} PMID 8121398</ref><ref name='S000046523'>Nadkarni AK, et al. (1995) Differential biochemical regulation of the URA7- and URA8-encoded CTP synthetases from Saccharomyces cerevisiae. J Biol Chem 270(42):24982-8 {{SGDpaper|S000046523}} PMID 7559626</ref><ref name='S000049478'>Ostrander DB, et al. (1998) Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae. J Biol Chem 273(30):18992-9001 {{SGDpaper|S000049478}} PMID 9668079</ref><ref name='S000051954'>Ozier-Kalogeropoulos O, et al. (1991) Cloning, sequencing and characterization of the Saccharomyces cerevisiae URA7 gene encoding CTP synthetase. Mol Gen Genet 231(1):7-16 {{SGDpaper|S000051954}} PMID 1753946</ref><ref name='S000065646'>McDonough VM, et al. (1995) Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by CTP. J Biol Chem 270(32):18774-80 |
| − | {{SGDpaper| | + | {{SGDpaper|S000065646}} PMID 7642527</ref> |
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Revision as of 04:40, 18 December 2008
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBL039C |
| Gene name | URA7 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:145731..143992 |
| Primary SGDID | S000000135 |
Description of YBL039C: Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis[1][2][3][4][5][6]
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References
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- Jump up ↑ Yang WL, et al. (1994) Purification and characterization of CTP synthetase, the product of the URA7 gene in Saccharomyces cerevisiae. Biochemistry 33(35):10785-93 SGD PMID 8075080
- Jump up ↑ Ozier-Kalogeropoulos O, et al. (1994) Use of synthetic lethal mutants to clone and characterize a novel CTP synthetase gene in Saccharomyces cerevisiae. Mol Gen Genet 242(4):431-9 SGD PMID 8121398
- Jump up ↑ Nadkarni AK, et al. (1995) Differential biochemical regulation of the URA7- and URA8-encoded CTP synthetases from Saccharomyces cerevisiae. J Biol Chem 270(42):24982-8 SGD PMID 7559626
- Jump up ↑ Ostrander DB, et al. (1998) Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae. J Biol Chem 273(30):18992-9001 SGD PMID 9668079
- Jump up ↑ Ozier-Kalogeropoulos O, et al. (1991) Cloning, sequencing and characterization of the Saccharomyces cerevisiae URA7 gene encoding CTP synthetase. Mol Gen Genet 231(1):7-16 SGD PMID 1753946
- Jump up ↑ McDonough VM, et al. (1995) Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by CTP. J Biol Chem 270(32):18774-80 SGD PMID 7642527
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