Difference between revisions of "YGL122C"
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| − | '''Description of YGL122C:''' Nuclear polyadenylated RNA-binding protein; autoregulates mRNA levels; related to human hnRNPs; | + | '''Description of YGL122C:''' Nuclear polyadenylated RNA-binding protein required for nuclear mRNA export and poly(A) tail length control; binds nuclear pore protein Mlp1p; autoregulates mRNA levels; related to human hnRNPs; nuclear localization sequence binds Kap104p<ref name='S000127300'>Fasken MB, et al. (2008) Functional significance of the interaction between the mRNA-binding protein, Nab2, and the nuclear pore-associated protein, Mlp1, in mRNA export. J Biol Chem {{SGDpaper|S000127300}} PMID 18682389</ref><ref name='S000081206'>Roth KM, et al. (2005) The nuclear exosome contributes to autogenous control of NAB2 mRNA levels. Mol Cell Biol 25(5):1577-85 {{SGDpaper|S000081206}} PMID 15713618</ref><ref name='S000069963'>Hector RE, et al. (2002) Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export. EMBO J 21(7):1800-10 {{SGDpaper|S000069963}} PMID 11927564</ref><ref name='S000069418'>Green DM, et al. (2002) Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p. J Biol Chem 277(10):7752-60 {{SGDpaper|S000069418}} PMID 11779864</ref><ref name='S000047435'>Truant R, et al. (1998) Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein. Mol Cell Biol 18(3):1449-58 {{SGDpaper|S000047435}} PMID 9488461</ref><ref name='S000046325'>Anderson JT, et al. (1993) NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability. Mol Cell Biol 13(5):2730-41 {{SGDpaper|S000046325}} PMID 8474438</ref><ref name='S000039514'>Wilson SM, et al. (1994) Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. J Cell Biol 127(5):1173-84 |
{{SGDpaper|S000039514}} PMID 7962083</ref> | {{SGDpaper|S000039514}} PMID 7962083</ref> | ||
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Revision as of 14:05, 14 August 2008
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| Systematic name | YGL122C |
| Gene name | NAB2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:280529..278952 |
| Primary SGDID | S000003090 |
Description of YGL122C: Nuclear polyadenylated RNA-binding protein required for nuclear mRNA export and poly(A) tail length control; binds nuclear pore protein Mlp1p; autoregulates mRNA levels; related to human hnRNPs; nuclear localization sequence binds Kap104p[1][2][3][4][5][6][7]
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References
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- ↑ Fasken MB, et al. (2008) Functional significance of the interaction between the mRNA-binding protein, Nab2, and the nuclear pore-associated protein, Mlp1, in mRNA export. J Biol Chem SGD PMID 18682389
- ↑ Roth KM, et al. (2005) The nuclear exosome contributes to autogenous control of NAB2 mRNA levels. Mol Cell Biol 25(5):1577-85 SGD PMID 15713618
- ↑ Hector RE, et al. (2002) Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export. EMBO J 21(7):1800-10 SGD PMID 11927564
- ↑ Green DM, et al. (2002) Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p. J Biol Chem 277(10):7752-60 SGD PMID 11779864
- ↑ Truant R, et al. (1998) Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein. Mol Cell Biol 18(3):1449-58 SGD PMID 9488461
- ↑ Anderson JT, et al. (1993) NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability. Mol Cell Biol 13(5):2730-41 SGD PMID 8474438
- ↑ Wilson SM, et al. (1994) Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. J Cell Biol 127(5):1173-84 SGD PMID 7962083
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