Difference between revisions of "YKL212W"
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| − | '''Description of YKL212W:''' Phosphatidylinositol ( | + | '''Description of YKL212W:''' Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance<ref name='S000069028'>Schorr M, et al. (2001) The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase. Curr Biol 11(18):1421-6 {{SGDpaper|S000069028}} PMID 11566100</ref><ref name='S000055623'>Hughes WE, et al. (2000) SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases. J Biol Chem 275(2):801-8 {{SGDpaper|S000055623}} PMID 10625610</ref><ref name='S000045780'>Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 {{SGDpaper|S000045780}} PMID 10224048</ref><ref name='S000040606'>Whitters EA, et al. (1993) SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J Cell Biol 122(1):79-94 |
{{SGDpaper|S000040606}} PMID 8314848</ref> | {{SGDpaper|S000040606}} PMID 8314848</ref> | ||
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Revision as of 13:05, 26 June 2008
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| Systematic name | YKL212W |
| Gene name | SAC1 |
| Aliases | RSD1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:34544..36415 |
| Primary SGDID | S000001695 |
Description of YKL212W: Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance[1][2][3][4]
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References
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- ↑ Schorr M, et al. (2001) The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase. Curr Biol 11(18):1421-6 SGD PMID 11566100
- ↑ Hughes WE, et al. (2000) SAC1 encodes a regulated lipid phosphoinositide phosphatase, defects in which can be suppressed by the homologous Inp52p and Inp53p phosphatases. J Biol Chem 275(2):801-8 SGD PMID 10625610
- ↑ Guo S, et al. (1999) SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem 274(19):12990-5 SGD PMID 10224048
- ↑ Whitters EA, et al. (1993) SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J Cell Biol 122(1):79-94 SGD PMID 8314848
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