YPR164W - Revision history

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-'''Description of YPR164W:''' Subunit of an E3 ubiquitin ligase complex involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; regulates Ty1 transposition; involved with Rtt101p in nonfunctional rRNA decay<ref name='S000073328'>Araki Y, et al. (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80 {{SGDpaper|S000073328}} PMID 12694535</ref><ref name='S000125772'>Duro E, et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7(5):811-8 {{SGDpaper|S000125772}} PMID 18321796</ref><ref name='S000130114'>Fujii K, et al. (2009) A role for ubiquitin in the clearance of nonfunctional rRNAs. Genes Dev 23(8):963-74 {{SGDpaper|S000130114}} PMID 19390089</ref><ref name='S000069116'>Hryciw T, et al. (2002) MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae. Mol Genet Genomics 266(5):848-57 {{SGDpaper|S000069116}} PMID 11810260</ref><ref name='S000068874'>Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 {{SGDpaper|S000068874}} PMID 11779788</ref><ref name='S000127386'>Zaidi IW, et al. (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9(10):1034-40
+'''Description of YPR164W:''' Subunit of an E3 ubiquitin ligase complex involved in replication repair; stabilizes protein components of the replication fork such as the fork-pausing complex and leading strand polymerase, preventing fork collapse and promoting efficient recovery during replication stress; regulates Ty1 transposition; involved with Rtt101p in nonfunctional rRNA decay<ref name='S000073328'>Araki Y, et al. (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80 {{SGDpaper|S000073328}} PMID 12694535</ref><ref name='S000125772'>Duro E, et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7(5):811-8 {{SGDpaper|S000125772}} PMID 18321796</ref><ref name='S000130114'>Fujii K, et al. (2009) A role for ubiquitin in the clearance of nonfunctional rRNAs. Genes Dev 23(8):963-74 {{SGDpaper|S000130114}} PMID 19390089</ref><ref name='S000069116'>Hryciw T, et al. (2002) MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae. Mol Genet Genomics 266(5):848-57 {{SGDpaper|S000069116}} PMID 11810260</ref><ref name='S000068874'>Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 {{SGDpaper|S000068874}} PMID 11779788</ref><ref name='S000147764'>Vaisica JA, et al. (2011) Mms1 and Mms22 stabilize the replisome during replication stress. Mol Biol Cell 22(13):2396-408 {{SGDpaper|S000147764}} PMID 21593207</ref><ref name='S000127386'>Zaidi IW, et al. (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9(10):1034-40
   {{SGDpaper|S000127386}} PMID 18704118</ref>
 <br>

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006368 YPR164W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006368 YPR164W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''MMS1 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr XVI:870699..874922
+|nowrap| Chr XVI:870703..874926
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000006368

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 |}
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-'''Description of YPR164W:''' Subunit of an E3 ubiquitin ligase complex involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; regulates Ty1 transposition; involved with Rtt101p in nonfunctional rRNA decay<ref name='S000069116'>Hryciw T, et al. (2002) MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae. Mol Genet Genomics 266(5):848-57 {{SGDpaper|S000069116}} PMID 11810260</ref><ref name='S000068874'>Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 {{SGDpaper|S000068874}} PMID 11779788</ref><ref name='S000073328'>Araki Y, et al. (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80 {{SGDpaper|S000073328}} PMID 12694535</ref><ref name='S000130114'>Fujii K, et al. (2009) A role for ubiquitin in the clearance of nonfunctional rRNAs. Genes Dev 23(8):963-74 {{SGDpaper|S000130114}} PMID 19390089</ref><ref name='S000125772'>Duro E, et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7(5):811-8 {{SGDpaper|S000125772}} PMID 18321796</ref><ref name='S000127386'>Zaidi IW, et al. (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9(10):1034-40
+'''Description of YPR164W:''' Subunit of an E3 ubiquitin ligase complex involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; regulates Ty1 transposition; involved with Rtt101p in nonfunctional rRNA decay<ref name='S000073328'>Araki Y, et al. (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80 {{SGDpaper|S000073328}} PMID 12694535</ref><ref name='S000125772'>Duro E, et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7(5):811-8 {{SGDpaper|S000125772}} PMID 18321796</ref><ref name='S000130114'>Fujii K, et al. (2009) A role for ubiquitin in the clearance of nonfunctional rRNAs. Genes Dev 23(8):963-74 {{SGDpaper|S000130114}} PMID 19390089</ref><ref name='S000069116'>Hryciw T, et al. (2002) MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae. Mol Genet Genomics 266(5):848-57 {{SGDpaper|S000069116}} PMID 11810260</ref><ref name='S000068874'>Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 {{SGDpaper|S000068874}} PMID 11779788</ref><ref name='S000127386'>Zaidi IW, et al. (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9(10):1034-40
   {{SGDpaper|S000127386}} PMID 18704118</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YPR164W:''' Protein that acts with Mms22p in a repair pathway that may be involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; implicated in regulation of Ty1 transposition<ref name='S000069116'>Hryciw T, et al. (2002) MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae. Mol Genet Genomics 266(5):848-57 {{SGDpaper|S000069116}} PMID 11810260</ref><ref name='S000068874'>Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 {{SGDpaper|S000068874}} PMID 11779788</ref><ref name='S000073328'>Araki Y, et al. (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80 {{SGDpaper|S000073328}} PMID 12694535</ref><ref name='S000125772'>Duro E, et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7(5):811-8
+'''Description of YPR164W:''' Subunit of an E3 ubiquitin ligase complex involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; regulates Ty1 transposition; involved with Rtt101p in nonfunctional rRNA decay<ref name='S000069116'>Hryciw T, et al. (2002) MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae. Mol Genet Genomics 266(5):848-57 {{SGDpaper|S000069116}} PMID 11810260</ref><ref name='S000068874'>Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 {{SGDpaper|S000068874}} PMID 11779788</ref><ref name='S000073328'>Araki Y, et al. (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80 {{SGDpaper|S000073328}} PMID 12694535</ref><ref name='S000130114'>Fujii K, et al. (2009) A role for ubiquitin in the clearance of nonfunctional rRNAs. Genes Dev 23(8):963-74 {{SGDpaper|S000130114}} PMID 19390089</ref><ref name='S000125772'>Duro E, et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7(5):811-8 {{SGDpaper|S000125772}} PMID 18321796</ref><ref name='S000127386'>Zaidi IW, et al. (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9(10):1034-40
-  {{SGDpaper|S000125772}} PMID 18321796</ref>
+  {{SGDpaper|S000127386}} PMID 18704118</ref>
 <br>
 <br>

← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
		+	-->

	<protect>		<protect>

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XVI:870699..874922
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 ==Community Commentary==
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