YOR038C - Revision history

SGDwikiBot: Automated import of articles

2012-01-23T14:45:42Z

Automated import of articles

SGDwikiBot: Automated import of articles

2010-02-25T21:05:30Z

Automated import of articles

SGDwikiBot: Automated import of articles

2009-03-31T21:05:35Z

Automated import of articles

SGDwikiBot: Automated import of articles

2009-02-26T14:21:46Z

Automated import of articles

SGDwikiBot: Automated import of articles

2007-02-27T15:46:18Z

Automated import of articles

SGDwikiBot: Automated import of articles

2007-02-21T20:02:26Z

Automated import of articles

SGDwikiBot: Automated import of articles

2007-01-30T15:18:09Z

Automated import of articles

SGDwikiBot: Automated import of articles

2007-01-23T15:20:43Z

Automated import of articles

New page

{{PageTop}}
{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR038C YOR038C]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HIR2 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''SPT1''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XV:405388..402761
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3, and H4 genes; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 {{SGDpaper|S000065877}} PMID 11412995</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67
{{SGDpaper|S000039248}} PMID 9504914</ref>
 
 
 
 

__TOC__
==Community Commentary==
{{CommentaryHelp}}

==References==

{{RefHelp}}

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YOR038C:''' Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67 {{SGDpaper|S000039248}} PMID 9504914</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000087068'>Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 {{SGDpaper|S000087068}} PMID 16264190</ref><ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73
+'''Description of YOR038C:''' Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67 {{SGDpaper|S000039248}} PMID 9504914</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000087068'>Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 {{SGDpaper|S000087068}} PMID 16264190</ref><ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 {{SGDpaper|S000065877}} PMID 11412995</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52
- {{SGDpaper|S000065877}} PMID 11412995</ref>
+ {{SGDpaper|S000055143}} PMID 9001207</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YOR038C:''' Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000087068'>Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 {{SGDpaper|S000087068}} PMID 16264190</ref><ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 {{SGDpaper|S000065877}} PMID 11412995</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67
+'''Description of YOR038C:''' Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67 {{SGDpaper|S000039248}} PMID 9504914</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000087068'>Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 {{SGDpaper|S000087068}} PMID 16264190</ref><ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73
-  {{SGDpaper|S000039248}} PMID 9504914</ref>
+  {{SGDpaper|S000065877}} PMID 11412995</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YOR038C:''' Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3, and H4 genes; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 {{SGDpaper|S000065877}} PMID 11412995</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67
+'''Description of YOR038C:''' Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000087068'>Prochasson P, et al. (2005) The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF. Genes Dev 19(21):2534-9 {{SGDpaper|S000087068}} PMID 16264190</ref><ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 {{SGDpaper|S000065877}} PMID 11412995</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67
   {{SGDpaper|S000039248}} PMID 9504914</ref>
 <br>

← Older revision		Revision as of 20:02, 21 February 2007
Line 28:		Line 28:
	{{CommentaryHelp}}		{{CommentaryHelp}}

		+
		+
		+
		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
		+	<!--
		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
		+	-->

	<protect>		<protect>

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005564 YOR038C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005564 YOR038C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''HIR2 ''

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YOR038C YOR038C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005564 YOR038C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''HIR2 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XV:405388..402761
 |}
 <br>
-'''Description of {{PAGENAME}}:''' Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3, and H4 genes; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 {{SGDpaper|S000065877}} PMID 11412995</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67
+'''Description of YOR038C:''' Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3, and H4 genes; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p<ref name='S000065877'>Sharp JA, et al. (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11(7):463-73 {{SGDpaper|S000065877}} PMID 11412995</ref><ref name='S000055143'>Spector MS, et al. (1997) Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol 17(2):545-52 {{SGDpaper|S000055143}} PMID 9001207</ref><ref name='S000048249'>Sherwood PW, et al. (1993) Characterization of HIR1 and HIR2, two genes required for regulation of histone gene transcription in Saccharomyces cerevisiae. Mol Cell Biol 13(1):28-38 {{SGDpaper|S000048249}} PMID 8417331</ref><ref name='S000047900'>Dimova D, et al. (1999) A role for transcriptional repressors in targeting the yeast Swi/Snf complex. Mol Cell 4(1):75-83 {{SGDpaper|S000047900}} PMID 10445029</ref><ref name='S000043368'>Kaufman PD, et al. (1998) Hir proteins are required for position-dependent gene silencing in Saccharomyces cerevisiae in the absence of chromatin assembly factor I. Mol Cell Biol 18(8):4793-806 {{SGDpaper|S000043368}} PMID 9671489</ref><ref name='S000039248'>DeSilva H, et al. (1998) Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics 148(2):657-67
   {{SGDpaper|S000039248}} PMID 9504914</ref>
 <br>
@@ Line 37: / Line 39: @@
 J Biol Chem 278(5):3265-74</ref>
 -->
 <protect>

@@ Line 1: / Line 1: @@
 <!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 {{PageTop}}
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
@@ Line 13: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XV:405388..402761
 |}
 <br>
@@ Line 23: / Line 22: @@
 <br>
 <br>
+<br>
 __TOC__
 ==Community Commentary==
 {{CommentaryHelp}}
 ==References==
 <!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 {{RefHelp}}