YNL224C - Revision history

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@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005168 YNL224C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005168 YNL224C]
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''SQS1 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr XIV:227100..224797
+|nowrap| Chr XIV:227099..224796
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000005168

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YNL224C:''' Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles<ref name='S000114899'>Lebaron S, et al. (2005) The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol 25(21):9269-82 {{SGDpaper|S000114899}} PMID 16227579</ref><ref name='S000118279'>Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 {{SGDpaper|S000118279}} PMID 16945917</ref><ref name='S000132276'>Lebaron S, et al. (2009) The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis. EMBO J 28(24):3808-19 {{SGDpaper|S000132276}} PMID 19927118</ref><ref name='S000131898'>Pertschy B, et al. (2009) RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem 284(50):35079-91
+'''Description of YNL224C:''' Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles<ref name='S000114899'>Lebaron S, et al. (2005) The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol 25(21):9269-82 {{SGDpaper|S000114899}} PMID 16227579</ref><ref name='S000132276'>Lebaron S, et al. (2009) The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis. EMBO J 28(24):3808-19 {{SGDpaper|S000132276}} PMID 19927118</ref><ref name='S000118279'>Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 {{SGDpaper|S000118279}} PMID 16945917</ref><ref name='S000131898'>Pertschy B, et al. (2009) RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem 284(50):35079-91
   {{SGDpaper|S000131898}} PMID 19801658</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YNL224C:''' Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles<ref name='S000114899'>Lebaron S, et al. (2005) The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol 25(21):9269-82 {{SGDpaper|S000114899}} PMID 16227579</ref><ref name='S000118279'>Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 {{SGDpaper|S000118279}} PMID 16945917</ref><ref name='S000132276'>Lebaron S, et al. (2009) The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis. EMBO J () {{SGDpaper|S000132276}} PMID 19927118</ref><ref name='S000131898'>Pertschy B, et al. (2009) RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem 284(50):35079-91
+'''Description of YNL224C:''' Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles<ref name='S000114899'>Lebaron S, et al. (2005) The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol 25(21):9269-82 {{SGDpaper|S000114899}} PMID 16227579</ref><ref name='S000118279'>Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 {{SGDpaper|S000118279}} PMID 16945917</ref><ref name='S000132276'>Lebaron S, et al. (2009) The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis. EMBO J 28(24):3808-19 {{SGDpaper|S000132276}} PMID 19927118</ref><ref name='S000131898'>Pertschy B, et al. (2009) RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem 284(50):35079-91
   {{SGDpaper|S000131898}} PMID 19801658</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YNL224C:''' Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles<ref name='S000114899'>Lebaron S, et al. (2005) The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol 25(21):9269-82 {{SGDpaper|S000114899}} PMID 16227579</ref><ref name='S000118279'>Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 {{SGDpaper|S000118279}} PMID 16945917</ref><ref name='S000132276'>Lebaron S, et al. (2009) The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis. EMBO J () {{SGDpaper|S000132276}} PMID 19927118</ref><ref name='S000131898'>Pertschy B, et al. (2009) RNA helicase Prp43 and its co-factor Pfa1 promote 20S to 18S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem
+'''Description of YNL224C:''' Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles<ref name='S000114899'>Lebaron S, et al. (2005) The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol 25(21):9269-82 {{SGDpaper|S000114899}} PMID 16227579</ref><ref name='S000118279'>Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 {{SGDpaper|S000118279}} PMID 16945917</ref><ref name='S000132276'>Lebaron S, et al. (2009) The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis. EMBO J () {{SGDpaper|S000132276}} PMID 19927118</ref><ref name='S000131898'>Pertschy B, et al. (2009) RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem 284(50):35079-91
   {{SGDpaper|S000131898}} PMID 19801658</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YNL224C:''' Protein of unknown function; overexpression antagonizes the suppression of splicing defects by spp382 mutants; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus<ref name='S000118279'>Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 {{SGDpaper|S000118279}} PMID 16945917</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
+'''Description of YNL224C:''' Protein that acts with Prp43p to stimulate 18srRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-40S ribosomal particles<ref name='S000114899'>Lebaron S, et al. (2005) The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol 25(21):9269-82 {{SGDpaper|S000114899}} PMID 16227579</ref><ref name='S000118279'>Pandit S, et al. (2006) Inhibition of a spliceosome turnover pathway suppresses splicing defects. Proc Natl Acad Sci U S A 103(37):13700-5 {{SGDpaper|S000118279}} PMID 16945917</ref><ref name='S000131898'>Pertschy B, et al. (2009) RNA helicase Prp43 and its co-factor Pfa1 promote 20S to 18S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem
-  {{SGDpaper|S000074185}} PMID 14562095</ref>
+  {{SGDpaper|S000131898}} PMID 19801658</ref>
 <br>
 <br>

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''SQS1 ''
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||'' ''
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''PFA1''
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''           || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]