YNL072W - Revision history

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2011-02-03T21:05:35Z

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2007-02-27T15:46:16Z

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005016 YNL072W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005016 YNL072W]
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''RNH201 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr XIV:490319..491242
+|nowrap| Chr XIV:490317..491240
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000005016

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 |}
 <br>
-'''Description of YNL072W:''' Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; homolog of RNAse HI (the S. cerevisiae homolog of mammalian RNAse HII is RNH1); related to human AGS4 that causes Aicardi-Goutieres syndrome<ref name='S000128478'>Crow YJ, et al. (2006) Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection. Nat Genet 38(8):910-6 {{SGDpaper|S000128478}} PMID 16845400</ref><ref name='S000050269'>Frank P, et al. (1998) Yeast RNase H(35) is the counterpart of the mammalian RNase HI, and is evolutionarily related to prokaryotic RNase HII. FEBS Lett 421(1):23-6 {{SGDpaper|S000050269}} PMID 9462832</ref><ref name='S000048942'>Qiu J, et al. (1999) Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol Cell Biol 19(12):8361-71
+'''Description of YNL072W:''' Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis and errant ribonucleotides misincorporated during DNA replication; homolog of RNAse HI; related to human AGS4 which causes Aicardi-Goutieres syndrome<ref name='S000128478'>Crow YJ, et al. (2006) Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection. Nat Genet 38(8):910-6 {{SGDpaper|S000128478}} PMID 16845400</ref><ref name='S000050269'>Frank P, et al. (1998) Yeast RNase H(35) is the counterpart of the mammalian RNase HI, and is evolutionarily related to prokaryotic RNase HII. FEBS Lett 421(1):23-6 {{SGDpaper|S000050269}} PMID 9462832</ref><ref name='S000136054'>Nick McElhinny SA, et al. (2010) Genome instability due to ribonucleotide incorporation into DNA. Nat Chem Biol 6(10):774-81 {{SGDpaper|S000136054}} PMID 20729855</ref><ref name='S000048942'>Qiu J, et al. (1999) Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol Cell Biol 19(12):8361-71
   {{SGDpaper|S000048942}} PMID 10567561</ref>
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 |}
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-'''Description of YNL072W:''' Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; homolog of RNAse HI (the S. cerevisiae homolog of mammalian RNAse HII is RNH1); related to human AGS4 that causes Aicardi-Goutieres syndrome<ref name='S000048942'>Qiu J, et al. (1999) Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol Cell Biol 19(12):8361-71 {{SGDpaper|S000048942}} PMID 10567561</ref><ref name='S000050269'>Frank P, et al. (1998) Yeast RNase H(35) is the counterpart of the mammalian RNase HI, and is evolutionarily related to prokaryotic RNase HII. FEBS Lett 421(1):23-6 {{SGDpaper|S000050269}} PMID 9462832</ref><ref name='S000128478'>Crow YJ, et al. (2006) Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection. Nat Genet 38(8):910-6
+'''Description of YNL072W:''' Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; homolog of RNAse HI (the S. cerevisiae homolog of mammalian RNAse HII is RNH1); related to human AGS4 that causes Aicardi-Goutieres syndrome<ref name='S000128478'>Crow YJ, et al. (2006) Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection. Nat Genet 38(8):910-6 {{SGDpaper|S000128478}} PMID 16845400</ref><ref name='S000050269'>Frank P, et al. (1998) Yeast RNase H(35) is the counterpart of the mammalian RNase HI, and is evolutionarily related to prokaryotic RNase HII. FEBS Lett 421(1):23-6 {{SGDpaper|S000050269}} PMID 9462832</ref><ref name='S000048942'>Qiu J, et al. (1999) Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol Cell Biol 19(12):8361-71
-  {{SGDpaper|S000128478}} PMID 16845400</ref>
+  {{SGDpaper|S000048942}} PMID 10567561</ref>
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr XIV:490318..491241
+|nowrap| Chr XIV:490319..491242
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000005016

← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
		+	-->

	<protect>		<protect>

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 ==Community Commentary==
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 ==References==
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