YML106W - Revision history

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{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YML106W YML106W]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''URA5 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''PYR5''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIII:56773..57453
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' One of two orotate phosphoribosyltransferase isozymes (see also URA10) that catalyze the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate<ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem (Tokyo) 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62
{{SGDpaper|S000050796}} PMID 2651891</ref>
 
 
 
 

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==Community Commentary==
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==References==

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 <br>
-'''Description of YML106W:''' Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10<ref name='S000048197'>de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11 {{SGDpaper|S000048197}} PMID 2182197</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 {{SGDpaper|S000050796}} PMID 2651891</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62
+'''Description of YML106W:''' Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10<ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 {{SGDpaper|S000050796}} PMID 2651891</ref><ref name='S000048197'>de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11
-  {{SGDpaper|S000081430}} PMID 5094209</ref>
+  {{SGDpaper|S000048197}} PMID 2182197</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YML106W:''' Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10<ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 {{SGDpaper|S000050796}} PMID 2651891</ref><ref name='S000048197'>de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11
+'''Description of YML106W:''' Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10<ref name='S000048197'>de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11 {{SGDpaper|S000048197}} PMID 2182197</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 {{SGDpaper|S000050796}} PMID 2651891</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62
-  {{SGDpaper|S000048197}} PMID 2182197</ref>
+  {{SGDpaper|S000081430}} PMID 5094209</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YML106W:''' One of two orotate phosphoribosyltransferase isozymes (see also URA10) that catalyze the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate<ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem (Tokyo) 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62
+'''Description of YML106W:''' Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10<ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 {{SGDpaper|S000050796}} PMID 2651891</ref><ref name='S000048197'>de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11
-  {{SGDpaper|S000050796}} PMID 2651891</ref>
+  {{SGDpaper|S000048197}} PMID 2182197</ref>
 <br>
 <br>

← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
		+	<!--
		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004574 YML106W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004574 YML106W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''URA5 ''

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YML106W YML106W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004574 YML106W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''URA5 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XIII:56773..57453
 |}
 <br>
-'''Description of {{PAGENAME}}:''' One of two orotate phosphoribosyltransferase isozymes (see also URA10) that catalyze the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate<ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem (Tokyo) 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62
+'''Description of YML106W:''' One of two orotate phosphoribosyltransferase isozymes (see also URA10) that catalyze the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate<ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem (Tokyo) 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62
   {{SGDpaper|S000050796}} PMID 2651891</ref>
 <br>
@@ Line 37: / Line 39: @@
 J Biol Chem 278(5):3265-74</ref>
 -->
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XIII:56773..57453
 |}
 <br>
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 __TOC__
 ==Community Commentary==
 {{CommentaryHelp}}
 ==References==
 <!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 {{RefHelp}}