YML102W - Revision history

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{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YML102W YML102W]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CAC2 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIII:68294..69700
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans<ref name='S000070370'>Krude T (2002) Chromatin assembly: the kinetochore connection. Curr Biol 12(7):R256-8 {{SGDpaper|S000070370}} PMID 11937044</ref><ref name='S000048516'>Kaufman PD, et al. (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev 11(3):345-57 {{SGDpaper|S000048516}} PMID 9030687</ref><ref name='S000047698'>Enomoto S and Berman J (1998) Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 12(2):219-32
{{SGDpaper|S000047698}} PMID 9436982</ref>
 
 
 
 

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==Community Commentary==
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==References==

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-'''Description of YML102W:''' Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans<ref name='S000047698'>Enomoto S and Berman J (1998) Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 12(2):219-32 {{SGDpaper|S000047698}} PMID 9436982</ref><ref name='S000048516'>Kaufman PD, et al. (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev 11(3):345-57 {{SGDpaper|S000048516}} PMID 9030687</ref><ref name='S000070370'>Krude T (2002) Chromatin assembly: the kinetochore connection. Curr Biol 12(7):R256-8
+'''Description of YML102W:''' Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p; chromatin assembly by CAF-1 is important for multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure; deactivation of the DNA damage checkpoint after DNA repair; and chromatin dynamics during transcription<ref name='S000047698'>Enomoto S and Berman J (1998) Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 12(2):219-32 {{SGDpaper|S000047698}} PMID 9436982</ref><ref name='S000053371'>Game JC and Kaufman PD (1999) Role of Saccharomyces cerevisiae chromatin assembly factor-I in repair of ultraviolet radiation damage in vivo. Genetics 151(2):485-97 {{SGDpaper|S000053371}} PMID 9927445</ref><ref name='S000048516'>Kaufman PD, et al. (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev 11(3):345-57 {{SGDpaper|S000048516}} PMID 9030687</ref><ref name='S000130078'>Kim HJ, et al. (2009) Potential role of the histone chaperone, CAF-1, in transcription. BMB Rep 42(4):227-31 {{SGDpaper|S000130078}} PMID 19403047</ref><ref name='S000129017'>Kim JA and Haber JE (2009) Chromatin assembly factors Asf1 and CAF-1 have overlapping roles in deactivating the DNA damage checkpoint when DNA repair is complete. Proc Natl Acad Sci U S A 106(4):1151-6 {{SGDpaper|S000129017}} PMID 19164567</ref><ref name='S000070370'>Krude T (2002) Chromatin assembly: the kinetochore connection. Curr Biol 12(7):R256-8 {{SGDpaper|S000070370}} PMID 11937044</ref><ref name='S000069112'>Sharp JA, et al. (2002) Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae. Genes Dev 16(1):85-100 {{SGDpaper|S000069112}} PMID 11782447</ref><ref name='S000054483'>Smith JS, et al. (1999) A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol Cell Biol 19(4):3184-97 {{SGDpaper|S000054483}} PMID 10082585</ref><ref name='S000080322'>Zabaronick SR and Tyler JK (2005) The histone chaperone anti-silencing function 1 is a global regulator of transcription independent of passage through S phase. Mol Cell Biol 25(2):652-60 {{SGDpaper|S000080322}} PMID 15632066</ref><ref name='S000114594'>Zhou H, et al. (2006) Chromatin assembly factor 1 interacts with histone H3 methylated at lysine 79 in the processes of epigenetic silencing and DNA repair. Biochemistry 45(9):2852-61
-  {{SGDpaper|S000070370}} PMID 11937044</ref>
+  {{SGDpaper|S000114594}} PMID 16503640</ref>
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 |}
 <br>
-'''Description of YML102W:''' Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans<ref name='S000070370'>Krude T (2002) Chromatin assembly: the kinetochore connection. Curr Biol 12(7):R256-8 {{SGDpaper|S000070370}} PMID 11937044</ref><ref name='S000048516'>Kaufman PD, et al. (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev 11(3):345-57 {{SGDpaper|S000048516}} PMID 9030687</ref><ref name='S000047698'>Enomoto S and Berman J (1998) Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 12(2):219-32
+'''Description of YML102W:''' Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans<ref name='S000047698'>Enomoto S and Berman J (1998) Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 12(2):219-32 {{SGDpaper|S000047698}} PMID 9436982</ref><ref name='S000048516'>Kaufman PD, et al. (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev 11(3):345-57 {{SGDpaper|S000048516}} PMID 9030687</ref><ref name='S000070370'>Krude T (2002) Chromatin assembly: the kinetochore connection. Curr Biol 12(7):R256-8
-  {{SGDpaper|S000047698}} PMID 9436982</ref>
+  {{SGDpaper|S000070370}} PMID 11937044</ref>
 <br>
 <br>

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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004570 YML102W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004570 YML102W]
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''CAC2 ''

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YML102W YML102W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004570 YML102W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''CAC2 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XIII:68294..69700
 |}
 <br>
-'''Description of {{PAGENAME}}:''' Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans<ref name='S000070370'>Krude T (2002) Chromatin assembly: the kinetochore connection. Curr Biol 12(7):R256-8 {{SGDpaper|S000070370}} PMID 11937044</ref><ref name='S000048516'>Kaufman PD, et al. (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev 11(3):345-57 {{SGDpaper|S000048516}} PMID 9030687</ref><ref name='S000047698'>Enomoto S and Berman J (1998) Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 12(2):219-32
+'''Description of YML102W:''' Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans<ref name='S000070370'>Krude T (2002) Chromatin assembly: the kinetochore connection. Curr Biol 12(7):R256-8 {{SGDpaper|S000070370}} PMID 11937044</ref><ref name='S000048516'>Kaufman PD, et al. (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev 11(3):345-57 {{SGDpaper|S000048516}} PMID 9030687</ref><ref name='S000047698'>Enomoto S and Berman J (1998) Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 12(2):219-32
   {{SGDpaper|S000047698}} PMID 9436982</ref>
 <br>
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 J Biol Chem 278(5):3265-74</ref>
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XIII:68294..69700
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 ==Community Commentary==
 {{CommentaryHelp}}
 ==References==
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 {{RefHelp}}