YML034W - Revision history

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004497 YML034W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004497 YML034W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''SRC1 ''

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YML034W:''' Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; mutant has aneuploidy tolerance<ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910 {{SGDpaper|S000127665}} PMID 18762579</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54 {{SGDpaper|S000069006}} PMID 11754482</ref><ref name='S000136872'>Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83 {{SGDpaper|S000136872}} PMID 20850176</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
+'''Description of YML034W:''' Inner nuclear membrane protein; functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; alternative splicing of SRC1 pre-mRNA is promoted by Hub1p; mutant has aneuploidy tolerance<ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910 {{SGDpaper|S000127665}} PMID 18762579</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000145470'>Mishra SK, et al. (2011) Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature () {{SGDpaper|S000145470}} PMID 21614000</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54 {{SGDpaper|S000069006}} PMID 11754482</ref><ref name='S000136872'>Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83 {{SGDpaper|S000136872}} PMID 20850176</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
   {{SGDpaper|S000074306}} PMID 14574415</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YML034W:''' Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; possible role in chromatid segregation<ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910 {{SGDpaper|S000127665}} PMID 18762579</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54 {{SGDpaper|S000069006}} PMID 11754482</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
+'''Description of YML034W:''' Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; mutant has aneuploidy tolerance<ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910 {{SGDpaper|S000127665}} PMID 18762579</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54 {{SGDpaper|S000069006}} PMID 11754482</ref><ref name='S000136872'>Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83 {{SGDpaper|S000136872}} PMID 20850176</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
   {{SGDpaper|S000074306}} PMID 14574415</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YML034W:''' Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; possible role in chromatid segregation<ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54 {{SGDpaper|S000069006}} PMID 11754482</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910
+'''Description of YML034W:''' Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; possible role in chromatid segregation<ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910 {{SGDpaper|S000127665}} PMID 18762579</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54 {{SGDpaper|S000069006}} PMID 11754482</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
-  {{SGDpaper|S000127665}} PMID 18762579</ref>
+  {{SGDpaper|S000074306}} PMID 14574415</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YML034W:''' Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; possible role in chromatid segregation<ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910 {{SGDpaper|S000127665}} PMID 18762579</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54
+'''Description of YML034W:''' Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; possible role in chromatid segregation<ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54 {{SGDpaper|S000069006}} PMID 11754482</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910
-  {{SGDpaper|S000069006}} PMID 11754482</ref>
+  {{SGDpaper|S000127665}} PMID 18762579</ref>
 <br>
 <br>

@@ Line 8: / Line 8: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''SRC1 ''
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''YML033W''
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''HEH1, YML033W''
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''           || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YML034W:''' Protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54
+'''Description of YML034W:''' Inner nuclear membrane protein that functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; possible role in chromatid segregation<ref name='S000127665'>Grund SE, et al. (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910 {{SGDpaper|S000127665}} PMID 18762579</ref><ref name='S000123937'>King MC, et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442(7106):1003-7 {{SGDpaper|S000123937}} PMID 16929305</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54
   {{SGDpaper|S000069006}} PMID 11754482</ref>
 <br>

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YML034W YML034W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004497 YML034W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''SRC1 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XIII:209525..212155
 |}
 <br>
-'''Description of {{PAGENAME}}:''' Protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54
+'''Description of YML034W:''' Protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000069006'>Rodriguez-Navarro S, et al. (2002) SRC1: an intron-containing yeast gene involved in sister chromatid segregation. Yeast 19(1):43-54
   {{SGDpaper|S000069006}} PMID 11754482</ref>
 <br>
@@ Line 45: / Line 47: @@
 J Biol Chem 278(5):3265-74</ref>
 -->
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← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
		+	-->

	<protect>		<protect>

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XIII:209525..212155
 |}
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