YLR128W - Revision history

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{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR128W YLR128W]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''DCN1 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:398531..399434
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain<ref name='S000082188'>Kurz T, et al. (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature 435(7046):1257-61 {{SGDpaper|S000082188}} PMID 15988528</ref><ref name='S000059095'>Willer M, et al. (2000) Disruption and functional analysis of six ORFs on chromosome XII of saccharomyces cerevisiae: YLR124w, YLR125w, YLR126c, YLR127c, YLR128w and YLR129w. Yeast 16(15):1429-35
{{SGDpaper|S000059095}} PMID 11054824</ref>
 
 
 
 

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==Community Commentary==
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==References==

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr XII:398531..399434
+|nowrap| Chr XII:398530..399433
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000004118

@@ Line 18: / Line 18: @@
 |}
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-'''Description of YLR128W:''' Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain<ref name='S000059095'>Willer M, et al. (2000) Disruption and functional analysis of six ORFs on chromosome XII of saccharomyces cerevisiae: YLR124w, YLR125w, YLR126c, YLR127c, YLR128w and YLR129w. Yeast 16(15):1429-35 {{SGDpaper|S000059095}} PMID 11054824</ref><ref name='S000082188'>Kurz T, et al. (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature 435(7046):1257-61
+'''Description of YLR128W:''' Scaffold-type E3 ligase required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation<ref name='S000082188'>Kurz T, et al. (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature 435(7046):1257-61 {{SGDpaper|S000082188}} PMID 15988528</ref><ref name='S000125334'>Kurz T, et al. (2008) Dcn1 functions as a scaffold-type e3 ligase for cullin neddylation. Mol Cell 29(1):23-35
-  {{SGDpaper|S000082188}} PMID 15988528</ref>
+  {{SGDpaper|S000125334}} PMID 18206966</ref>
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 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YLR128W:''' Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain<ref name='S000082188'>Kurz T, et al. (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature 435(7046):1257-61 {{SGDpaper|S000082188}} PMID 15988528</ref><ref name='S000059095'>Willer M, et al. (2000) Disruption and functional analysis of six ORFs on chromosome XII of saccharomyces cerevisiae: YLR124w, YLR125w, YLR126c, YLR127c, YLR128w and YLR129w. Yeast 16(15):1429-35
+'''Description of YLR128W:''' Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain<ref name='S000059095'>Willer M, et al. (2000) Disruption and functional analysis of six ORFs on chromosome XII of saccharomyces cerevisiae: YLR124w, YLR125w, YLR126c, YLR127c, YLR128w and YLR129w. Yeast 16(15):1429-35 {{SGDpaper|S000059095}} PMID 11054824</ref><ref name='S000082188'>Kurz T, et al. (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature 435(7046):1257-61
-  {{SGDpaper|S000059095}} PMID 11054824</ref>
+  {{SGDpaper|S000082188}} PMID 15988528</ref>
 <br>
 <br>

← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
		+	-->

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 {|{{Prettytable}} align = 'right' width = '200px'
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-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004118 YLR128W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004118 YLR128W]
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''DCN1 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr XII:398531..399434
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 ==Community Commentary==
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 ==References==
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