YJR135W-A - Revision history

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2011-02-03T21:05:45Z

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2007-02-27T15:46:26Z

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2007-02-21T20:02:17Z

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2007-01-30T15:18:00Z

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2007-01-23T15:20:37Z

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{{PageTop}}
{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJR135W-A YJR135W-A]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TIM8 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:676965..677228
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' Mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins; homolog of human DDP1 (deafness dystonia peptide 1) which is mutated in the X-linked Mohr-Tranebjaerg syndrome<ref name='S000065406'>Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80
{{SGDpaper|S000065406}} PMID 11405338</ref>
 
 
 
 

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==Community Commentary==
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==References==

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr X:676961..677224
+|nowrap| Chr X:676971..677234
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000007348

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-'''Description of YJR135W-A:''' Mitochondrial intermembrane space protein, forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome<ref name='S000043156'>Koehler CM, et al. (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A 96(5):2141-6 {{SGDpaper|S000043156}} PMID 10051608</ref><ref name='S000047441'>Leuenberger D, et al. (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22 {{SGDpaper|S000047441}} PMID 10469659</ref><ref name='S000065406'>Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80 {{SGDpaper|S000065406}} PMID 11405338</ref><ref name='S000131707'>Davis AJ, et al. (2007) The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import. Mol Biol Cell 18(2):475-86
+'''Description of YJR135W-A:''' Mitochondrial intermembrane space protein, forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome<ref name='S000065406'>Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80 {{SGDpaper|S000065406}} PMID 11405338</ref><ref name='S000131707'>Davis AJ, et al. (2007) The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import. Mol Biol Cell 18(2):475-86 {{SGDpaper|S000131707}} PMID 17122363</ref><ref name='S000043156'>Koehler CM, et al. (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A 96(5):2141-6 {{SGDpaper|S000043156}} PMID 10051608</ref><ref name='S000047441'>Leuenberger D, et al. (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22
-  {{SGDpaper|S000131707}} PMID 17122363</ref>
+  {{SGDpaper|S000047441}} PMID 10469659</ref>
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 |}
 <br>
-'''Description of YJR135W-A:''' Mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins; homolog of human DDP1 (deafness dystonia peptide 1) which is mutated in the X-linked Mohr-Tranebjaerg syndrome<ref name='S000065406'>Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80
+'''Description of YJR135W-A:''' Mitochondrial intermembrane space protein, forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome<ref name='S000043156'>Koehler CM, et al. (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A 96(5):2141-6 {{SGDpaper|S000043156}} PMID 10051608</ref><ref name='S000047441'>Leuenberger D, et al. (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22 {{SGDpaper|S000047441}} PMID 10469659</ref><ref name='S000065406'>Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80 {{SGDpaper|S000065406}} PMID 11405338</ref><ref name='S000131707'>Davis AJ, et al. (2007) The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import. Mol Biol Cell 18(2):475-86
-  {{SGDpaper|S000065406}} PMID 11405338</ref>
+  {{SGDpaper|S000131707}} PMID 17122363</ref>
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr X:676965..677228
+|nowrap| Chr X:676961..677224
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000007348

← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000007348 YJR135W-A]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000007348 YJR135W-A]
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''TIM8 ''

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 ==Community Commentary==
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