YJL208C - Revision history

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{{PageTop}}
{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJL208C YJL208C]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUC1 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:41183..40194
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has a role in mitochondrial recombination<ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
{{SGDpaper|S000045493}} PMID 2836792</ref>
 
 
 
 

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==Community Commentary==
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==References==

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 <br>
-'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312 {{SGDpaper|S000045493}} PMID 2836792</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6
+'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6 {{SGDpaper|S000122630}} PMID 17471024</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312 {{SGDpaper|S000045493}} PMID 2836792</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9
-  {{SGDpaper|S000122630}} PMID 17471024</ref>
+  {{SGDpaper|S000052577}} PMID 8087883</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6 {{SGDpaper|S000122630}} PMID 17471024</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
+'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312 {{SGDpaper|S000045493}} PMID 2836792</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6
-  {{SGDpaper|S000045493}} PMID 2836792</ref>
+  {{SGDpaper|S000122630}} PMID 17471024</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease g selectively kills polyploid cells. Cell Cycle 6(9):1072-6 {{SGDpaper|S000122630}} PMID 17471024</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
+'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle 6(9):1072-6 {{SGDpaper|S000122630}} PMID 17471024</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
   {{SGDpaper|S000045493}} PMID 2836792</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has a role in mitochondrial recombination and in apoptosis<ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
+'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy<ref name='S000122630'>Buttner S, et al. (2007) Depletion of endonuclease g selectively kills polyploid cells. Cell Cycle 6(9):1072-6 {{SGDpaper|S000122630}} PMID 17471024</ref><ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
   {{SGDpaper|S000045493}} PMID 2836792</ref>
 <br>

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJL208C YJL208C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003744 YJL208C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''NUC1 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr X:41183..40194
 |}
 <br>
-'''Description of {{PAGENAME}}:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has a role in mitochondrial recombination and in apoptosis<ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
+'''Description of YJL208C:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has a role in mitochondrial recombination and in apoptosis<ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
   {{SGDpaper|S000045493}} PMID 2836792</ref>
 <br>
@@ Line 37: / Line 39: @@
 J Biol Chem 278(5):3265-74</ref>
 -->
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 |}
 <br>
-'''Description of {{PAGENAME}}:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has a role in mitochondrial recombination<ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
+'''Description of {{PAGENAME}}:''' Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has a role in mitochondrial recombination and in apoptosis<ref name='S000120511'>Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 {{SGDpaper|S000120511}} PMID 17244531</ref><ref name='S000057053'>Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 {{SGDpaper|S000057053}} PMID 3286639</ref><ref name='S000052577'>Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 {{SGDpaper|S000052577}} PMID 8087883</ref><ref name='S000045493'>Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312
   {{SGDpaper|S000045493}} PMID 2836792</ref>
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr X:41183..40194
 |}
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 ==Community Commentary==
 {{CommentaryHelp}}
 ==References==
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 {{RefHelp}}