YGR206W - Revision history

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{{PageTop}}
{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGR206W YGR206W]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MVB12 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||'' ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Uncharacterized[[Category:ORF]][[Category:ORF, Uncharacterized]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:910437..910742
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' ESCRT-I subunit necessary for the efficient transport of cargo proteins to the vacuolar lumen; deletion mutant sensitive to rapamycin and nystatin; green fluorescent protein (GFP)-fusion protein localizes to endosome<ref name='S000119855'>Curtiss M, et al. (2006) Efficient Cargo Sorting by ESCRT-I and the Subsequent Release of ESCRT-I from MVBs Requires the Subunit Mvb12. Mol Biol Cell () {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
{{SGDpaper|S000071347}} PMID 12140549</ref>
 
 
 
 

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==Community Commentary==
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==References==

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@@ Line 13: / Line 13: @@
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr VII:910437..910742
+|nowrap| Chr VII:910432..910737
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000003438

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YGR206W:''' ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin<ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000119855'>Curtiss M, et al. (2007) Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000123193'>Chu T, et al. (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175(5):815-23
+'''Description of YGR206W:''' ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin<ref name='S000123193'>Chu T, et al. (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175(5):815-23 {{SGDpaper|S000123193}} PMID 17145965</ref><ref name='S000119855'>Curtiss M, et al. (2007) Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20
-  {{SGDpaper|S000123193}} PMID 17145965</ref>
+  {{SGDpaper|S000081669}} PMID 15883373</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YGR206W:''' ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin<ref name='S000123193'>Chu T, et al. (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175(5):815-23 {{SGDpaper|S000123193}} PMID 17145965</ref><ref name='S000119855'>Curtiss M, et al. (2007) Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
+'''Description of YGR206W:''' ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin<ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000119855'>Curtiss M, et al. (2007) Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000123193'>Chu T, et al. (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175(5):815-23
-  {{SGDpaper|S000071347}} PMID 12140549</ref>
+  {{SGDpaper|S000123193}} PMID 17145965</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YGR206W:''' ESCRT-I subunit necessary for the efficient transport of cargo proteins to the vacuolar lumen; deletion mutant sensitive to rapamycin and nystatin; green fluorescent protein (GFP)-fusion protein localizes to endosome<ref name='S000119855'>Curtiss M, et al. (2007) Efficient Cargo Sorting by ESCRT-I and the Subsequent Release of ESCRT-I from Multivesicular Bodies Requires the Subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
+'''Description of YGR206W:''' ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin<ref name='S000123193'>Chu T, et al. (2006) New component of ESCRT-I regulates endosomal sorting complex assembly. J Cell Biol 175(5):815-23 {{SGDpaper|S000123193}} PMID 17145965</ref><ref name='S000119855'>Curtiss M, et al. (2007) Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
   {{SGDpaper|S000071347}} PMID 12140549</ref>
 <br>

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGR206W YGR206W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003438 YGR206W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''MVB12 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr VII:910437..910742
 |}
 <br>
-'''Description of {{PAGENAME}}:''' ESCRT-I subunit necessary for the efficient transport of cargo proteins to the vacuolar lumen; deletion mutant sensitive to rapamycin and nystatin; green fluorescent protein (GFP)-fusion protein localizes to endosome<ref name='S000119855'>Curtiss M, et al. (2007) Efficient Cargo Sorting by ESCRT-I and the Subsequent Release of ESCRT-I from Multivesicular Bodies Requires the Subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
+'''Description of YGR206W:''' ESCRT-I subunit necessary for the efficient transport of cargo proteins to the vacuolar lumen; deletion mutant sensitive to rapamycin and nystatin; green fluorescent protein (GFP)-fusion protein localizes to endosome<ref name='S000119855'>Curtiss M, et al. (2007) Efficient Cargo Sorting by ESCRT-I and the Subsequent Release of ESCRT-I from Multivesicular Bodies Requires the Subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
   {{SGDpaper|S000071347}} PMID 12140549</ref>
 <br>
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 J Biol Chem 278(5):3265-74</ref>
 -->
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@@ Line 10: / Line 10: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||'' ''
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''           || ORF, Uncharacterized[[Category:ORF]][[Category:ORF, Uncharacterized]]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''           || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''

@@ Line 16: / Line 16: @@
 |}
 <br>
-'''Description of {{PAGENAME}}:''' ESCRT-I subunit necessary for the efficient transport of cargo proteins to the vacuolar lumen; deletion mutant sensitive to rapamycin and nystatin; green fluorescent protein (GFP)-fusion protein localizes to endosome<ref name='S000119855'>Curtiss M, et al. (2006) Efficient Cargo Sorting by ESCRT-I and the Subsequent Release of ESCRT-I from MVBs Requires the Subunit Mvb12. Mol Biol Cell () {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
+'''Description of {{PAGENAME}}:''' ESCRT-I subunit necessary for the efficient transport of cargo proteins to the vacuolar lumen; deletion mutant sensitive to rapamycin and nystatin; green fluorescent protein (GFP)-fusion protein localizes to endosome<ref name='S000119855'>Curtiss M, et al. (2007) Efficient Cargo Sorting by ESCRT-I and the Subsequent Release of ESCRT-I from Multivesicular Bodies Requires the Subunit Mvb12. Mol Biol Cell 18(2):636-45 {{SGDpaper|S000119855}} PMID 17135292</ref><ref name='S000081669'>Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 {{SGDpaper|S000081669}} PMID 15883373</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
   {{SGDpaper|S000071347}} PMID 12140549</ref>
 <br>
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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr VII:910437..910742
 |}
 <br>
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 <br>
 <br>
+<br>
 __TOC__
 ==Community Commentary==
 {{CommentaryHelp}}
 ==References==
 <!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 {{RefHelp}}