YGR202C - Revision history

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{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YGR202C YGR202C]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''PCT1 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''BSR2, CCT1''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:904753..903479
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding<ref name='S000064321'>Friesen JA, et al. (2001) Purification and kinetic characterization of CTP:phosphocholine cytidylyltransferase from Saccharomyces cerevisiae. Protein Expr Purif 21(1):141-8 {{SGDpaper|S000064321}} PMID 11162399</ref><ref name='S000059477'>Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 {{SGDpaper|S000059477}} PMID 11078727</ref><ref name='S000056938'>Tsukagoshi Y, et al. (1987) Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem 169(3):477-86 {{SGDpaper|S000056938}} PMID 2826147</ref><ref name='S000051159'>Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 {{SGDpaper|S000051159}} PMID 9642212</ref><ref name='S000045374'>Skinner HB, et al. (1995) The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A 92(1):112-6
{{SGDpaper|S000045374}} PMID 7816798</ref>
 
 
 
 

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==Community Commentary==
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==References==

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@@ Line 13: / Line 13: @@
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr VII:904753..903479
+|nowrap| Chr VII:904748..903474
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000003434

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YGR202C:''' Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding<ref name='S000045374'>Skinner HB, et al. (1995) The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A 92(1):112-6 {{SGDpaper|S000045374}} PMID 7816798</ref><ref name='S000051159'>Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 {{SGDpaper|S000051159}} PMID 9642212</ref><ref name='S000056938'>Tsukagoshi Y, et al. (1987) Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem 169(3):477-86 {{SGDpaper|S000056938}} PMID 2826147</ref><ref name='S000059477'>Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 {{SGDpaper|S000059477}} PMID 11078727</ref><ref name='S000064321'>Friesen JA, et al. (2001) Purification and kinetic characterization of CTP:phosphocholine cytidylyltransferase from Saccharomyces cerevisiae. Protein Expr Purif 21(1):141-8
+'''Description of YGR202C:''' Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding<ref name='S000059477'>Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 {{SGDpaper|S000059477}} PMID 11078727</ref><ref name='S000064321'>Friesen JA, et al. (2001) Purification and kinetic characterization of CTP:phosphocholine cytidylyltransferase from Saccharomyces cerevisiae. Protein Expr Purif 21(1):141-8 {{SGDpaper|S000064321}} PMID 11162399</ref><ref name='S000045374'>Skinner HB, et al. (1995) The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A 92(1):112-6 {{SGDpaper|S000045374}} PMID 7816798</ref><ref name='S000051159'>Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 {{SGDpaper|S000051159}} PMID 9642212</ref><ref name='S000056938'>Tsukagoshi Y, et al. (1987) Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem 169(3):477-86
- {{SGDpaper|S000064321}} PMID 11162399</ref>
+ {{SGDpaper|S000056938}} PMID 2826147</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YGR202C:''' Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding<ref name='S000064321'>Friesen JA, et al. (2001) Purification and kinetic characterization of CTP:phosphocholine cytidylyltransferase from Saccharomyces cerevisiae. Protein Expr Purif 21(1):141-8 {{SGDpaper|S000064321}} PMID 11162399</ref><ref name='S000059477'>Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 {{SGDpaper|S000059477}} PMID 11078727</ref><ref name='S000056938'>Tsukagoshi Y, et al. (1987) Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem 169(3):477-86 {{SGDpaper|S000056938}} PMID 2826147</ref><ref name='S000051159'>Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 {{SGDpaper|S000051159}} PMID 9642212</ref><ref name='S000045374'>Skinner HB, et al. (1995) The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A 92(1):112-6
+'''Description of YGR202C:''' Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding<ref name='S000045374'>Skinner HB, et al. (1995) The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A 92(1):112-6 {{SGDpaper|S000045374}} PMID 7816798</ref><ref name='S000051159'>Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 {{SGDpaper|S000051159}} PMID 9642212</ref><ref name='S000056938'>Tsukagoshi Y, et al. (1987) Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem 169(3):477-86 {{SGDpaper|S000056938}} PMID 2826147</ref><ref name='S000059477'>Dowd SR, et al. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. The role of the CDP-choline pathway. J Biol Chem 276(6):3756-63 {{SGDpaper|S000059477}} PMID 11078727</ref><ref name='S000064321'>Friesen JA, et al. (2001) Purification and kinetic characterization of CTP:phosphocholine cytidylyltransferase from Saccharomyces cerevisiae. Protein Expr Purif 21(1):141-8
-  {{SGDpaper|S000045374}} PMID 7816798</ref>
+  {{SGDpaper|S000064321}} PMID 11162399</ref>
 <br>
 <br>

← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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 {|{{Prettytable}} align = 'right' width = '200px'
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-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003434 YGR202C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003434 YGR202C]
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''PCT1 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr VII:904753..903479
 |}
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 ==Community Commentary==
 {{CommentaryHelp}}
 ==References==
 <!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 {{RefHelp}}