YGR146C - Revision history

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-'''Description of YGR146C:''' Protein of unknown function, affects chronological lifespan; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation<ref name='S000132475'>Azuma K, et al. (2009) Identification and Characterization of an Ecl1-Family Gene in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 73(12):2787-9 {{SGDpaper|S000132475}} PMID 19966476</ref><ref name='S000123213'>Dardalhon M, et al. (2007) Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS Yeast Res 7(6):866-878 {{SGDpaper|S000123213}} PMID 17608707</ref><ref name='S000082119'>Imazu H and Sakurai H (2005) Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock. Eukaryot Cell 4(6):1050-6 {{SGDpaper|S000082119}} PMID 15947197</ref><ref name='S000073710'>Rutherford JC, et al. (2003) Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements. J Biol Chem 278(30):27636-43
+'''Description of YGR146C:''' Protein of unknown function; mitochondrial-dependent role in the extension of chronological lifespan; overexpression increases oxygen consumption and respiratory activity while deletion results in reduced oxygen consumption under conditions of caloric restriction; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation<ref name='S000132475'>Azuma K, et al. (2009) Identification and Characterization of an Ecl1-Family Gene in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 73(12):2787-9 {{SGDpaper|S000132475}} PMID 19966476</ref><ref name='S000151336'>Azuma K, et al. (2012) Extension of Chronological Lifespan by ScEcl1 Depends on the Mitochondria in Saccharomyces cerevisiae. Biosci Biotechnol Biochem () {{SGDpaper|S000151336}} PMID 23047113</ref><ref name='S000123213'>Dardalhon M, et al. (2007) Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS Yeast Res 7(6):866-878 {{SGDpaper|S000123213}} PMID 17608707</ref><ref name='S000082119'>Imazu H and Sakurai H (2005) Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock. Eukaryot Cell 4(6):1050-6 {{SGDpaper|S000082119}} PMID 15947197</ref><ref name='S000073710'>Rutherford JC, et al. (2003) Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements. J Biol Chem 278(30):27636-43
   {{SGDpaper|S000073710}} PMID 12756250</ref>
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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003378 YGR146C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003378 YGR146C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''ECL1 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr VII:784863..784228
+|nowrap| Chr VII:784858..784223
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000003378

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 |}
 <br>
-'''Description of YGR146C:''' Protein of unknown function, affects chronological lifespan; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation<ref name='S000082119'>Imazu H and Sakurai H (2005) Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock. Eukaryot Cell 4(6):1050-6 {{SGDpaper|S000082119}} PMID 15947197</ref><ref name='S000073710'>Rutherford JC, et al. (2003) Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements. J Biol Chem 278(30):27636-43 {{SGDpaper|S000073710}} PMID 12756250</ref><ref name='S000123213'>Dardalhon M, et al. (2007) Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS Yeast Res 7(6):866-878 {{SGDpaper|S000123213}} PMID 17608707</ref><ref name='S000132475'>Azuma K, et al. (2009) Identification and Characterization of an Ecl1-Family Gene in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 73(12):2787-9
+'''Description of YGR146C:''' Protein of unknown function, affects chronological lifespan; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation<ref name='S000132475'>Azuma K, et al. (2009) Identification and Characterization of an Ecl1-Family Gene in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 73(12):2787-9 {{SGDpaper|S000132475}} PMID 19966476</ref><ref name='S000123213'>Dardalhon M, et al. (2007) Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS Yeast Res 7(6):866-878 {{SGDpaper|S000123213}} PMID 17608707</ref><ref name='S000082119'>Imazu H and Sakurai H (2005) Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock. Eukaryot Cell 4(6):1050-6 {{SGDpaper|S000082119}} PMID 15947197</ref><ref name='S000073710'>Rutherford JC, et al. (2003) Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements. J Biol Chem 278(30):27636-43
-  {{SGDpaper|S000132475}} PMID 19966476</ref>
+  {{SGDpaper|S000073710}} PMID 12756250</ref>
 <br>
 <br>

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 |}
 <br>
-'''Description of YGR146C:''' Protein of unknown function, affects chronological lifespan; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation<ref name='S000082119'>Imazu H and Sakurai H (2005) Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock. Eukaryot Cell 4(6):1050-6 {{SGDpaper|S000082119}} PMID 15947197</ref><ref name='S000073710'>Rutherford JC, et al. (2003) Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements. J Biol Chem 278(30):27636-43 {{SGDpaper|S000073710}} PMID 12756250</ref><ref name='S000123213'>Dardalhon M, et al. (2007) Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS Yeast Res 7(6):866-878 {{SGDpaper|S000123213}} PMID 17608707</ref><ref name='S000132475'>Azuma K, et al. (2009) Identification and Characterization of an Ecl1-Family Gene in Saccharomyces cerevisiae. Biosci Biotechnol Biochem ()
+'''Description of YGR146C:''' Protein of unknown function, affects chronological lifespan; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation<ref name='S000082119'>Imazu H and Sakurai H (2005) Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock. Eukaryot Cell 4(6):1050-6 {{SGDpaper|S000082119}} PMID 15947197</ref><ref name='S000073710'>Rutherford JC, et al. (2003) Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements. J Biol Chem 278(30):27636-43 {{SGDpaper|S000073710}} PMID 12756250</ref><ref name='S000123213'>Dardalhon M, et al. (2007) Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS Yeast Res 7(6):866-878 {{SGDpaper|S000123213}} PMID 17608707</ref><ref name='S000132475'>Azuma K, et al. (2009) Identification and Characterization of an Ecl1-Family Gene in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 73(12):2787-9
   {{SGDpaper|S000132475}} PMID 19966476</ref>
 <br>