YGR003W - Revision history

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@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003235 YGR003W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003235 YGR003W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''CUL3 ''

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YGR003W:''' Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21<ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 {{SGDpaper|S000042395}} PMID 9531531</ref><ref name='S000073416'>Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37 {{SGDpaper|S000073416}} PMID 12676951</ref><ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6
+'''Description of YGR003W:''' Ubiquitin-protein ligase, forms a complex with Elc1p that polyubiquitylates monoubiquitylated RNA polymerase II to trigger its proteolysis; cullin family member with similarity to Cdc53p and human CUL3<ref name='S000136358'>Harreman M, et al. (2009) Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation. Proc Natl Acad Sci U S A 106(49):20705-10 {{SGDpaper|S000136358}} PMID 19920177</ref><ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 {{SGDpaper|S000042395}} PMID 9531531</ref><ref name='S000073416'>Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37 {{SGDpaper|S000073416}} PMID 12676951</ref><ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6
   {{SGDpaper|S000120848}} PMID 17296727</ref>
 <br>

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 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr VII:500136..502370
+|nowrap| Chr VII:500132..502366
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000003235

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YGR003W:''' Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21<ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6 {{SGDpaper|S000120848}} PMID 17296727</ref><ref name='S000073416'>Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37 {{SGDpaper|S000073416}} PMID 12676951</ref><ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26
+'''Description of YGR003W:''' Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21<ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 {{SGDpaper|S000042395}} PMID 9531531</ref><ref name='S000073416'>Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37 {{SGDpaper|S000073416}} PMID 12676951</ref><ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6
-  {{SGDpaper|S000042395}} PMID 9531531</ref>
+  {{SGDpaper|S000120848}} PMID 17296727</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YGR003W:''' Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21<ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26 {{SGDpaper|S000042395}} PMID 9531531</ref><ref name='S000073416'>Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37 {{SGDpaper|S000073416}} PMID 12676951</ref><ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6
+'''Description of YGR003W:''' Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21<ref name='S000120848'>Ribar B, et al. (2007) ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells. Mol Cell Biol 27(8):3211-6 {{SGDpaper|S000120848}} PMID 17296727</ref><ref name='S000073416'>Michel JJ, et al. (2003) A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression. J Biol Chem 278(25):22828-37 {{SGDpaper|S000073416}} PMID 12676951</ref><ref name='S000042395'>Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26
-  {{SGDpaper|S000120848}} PMID 17296727</ref>
+  {{SGDpaper|S000042395}} PMID 9531531</ref>
 <br>
 <br>

← Older revision	Revision as of 23:20, 21 May 2007
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← Older revision		Revision as of 11:32, 21 May 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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