YFL038C - Revision history

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‎References

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@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001856 YFL038C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001856 YFL038C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''YPT1 ''

@@ Line 13: / Line 13: @@
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr VI:55985..55365
+|nowrap| Chr VI:55986..55366
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000001856

← Older revision		Revision as of 21:05, 13 October 2010
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	{{RefHelp}}		{{RefHelp}}
	</protect>		</protect>
−
−	~~A couple of comments on interactions of proteins with Ypt1:~~
−	1) TRS130 was incorrectly listed here as interacting with Ypt1 by yeast-2-hybrid. The reference listed (Morozova et al 2006) actually uses Ypt1 as a negative control for interaction between TRS130 and YPT31.
−
−	2) Trs20 and Trs33 were not shown to DIRECTLY interact with Ypt1. The reference for this interaction (Wang et al 2000) includes the following experiment: purified Ypt1 was incubated with yeast lysates, and the product of the pulldowns were probed with anti-Trs20 or anti-Trs33 antibodies. In this case, the interactions could be (and probably are) indirect.

← Older revision		Revision as of 19:00, 13 October 2010
Line 47:		Line 47:
	{{RefHelp}}		{{RefHelp}}
	</protect>		</protect>
		+
		+	A couple of comments on interactions of proteins with Ypt1:
		+	1) TRS130 was incorrectly listed here as interacting with Ypt1 by yeast-2-hybrid. The reference listed (Morozova et al 2006) actually uses Ypt1 as a negative control for interaction between TRS130 and YPT31.
		+
		+	2) Trs20 and Trs33 were not shown to DIRECTLY interact with Ypt1. The reference for this interaction (Wang et al 2000) includes the following experiment: purified Ypt1 was incubated with yeast lysates, and the product of the pulldowns were probed with anti-Trs20 or anti-Trs33 antibodies. In this case, the interactions could be (and probably are) indirect.

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 |}
 <br>
-'''Description of YFL038C:''' Rab family small GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)<ref name='S000049341'>Miaczynska M, et al. (1997) The yeast Rab escort protein binds intracellular membranes in vivo and in vitro. J Biol Chem 272(27):16972-7 {{SGDpaper|S000049341}} PMID 9202009</ref><ref name='S000069558'>Morsomme P and Riezman H (2002) The Rab GTPase Ypt1p and tethering factors couple protein sorting at the ER to vesicle targeting to the Golgi apparatus. Dev Cell 2(3):307-17
+'''Description of YFL038C:''' Rab family GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)<ref name='S000049341'>Miaczynska M, et al. (1997) The yeast Rab escort protein binds intracellular membranes in vivo and in vitro. J Biol Chem 272(27):16972-7 {{SGDpaper|S000049341}} PMID 9202009</ref><ref name='S000069558'>Morsomme P and Riezman H (2002) The Rab GTPase Ypt1p and tethering factors couple protein sorting at the ER to vesicle targeting to the Golgi apparatus. Dev Cell 2(3):307-17
   {{SGDpaper|S000069558}} PMID 11879636</ref>
 <br>