YEL034W - Revision history

SGDwikiBot: Automated import of articles

2012-09-20T21:05:14Z

Automated import of articles

SGDwikiBot: Automated import of articles

2012-01-23T14:45:19Z

Automated import of articles

SGDwikiBot: Automated import of articles

2011-04-23T21:05:17Z

Automated import of articles

SGDwikiBot: Automated import of articles

2011-04-13T21:05:14Z

Automated import of articles

SGDwikiBot: Automated import of articles

2010-02-25T21:05:13Z

Automated import of articles

SGDwikiBot: Automated import of articles

2009-06-19T21:05:11Z

Automated import of articles

SGDwikiBot: Automated import of articles

2009-05-26T21:05:11Z

Automated import of articles

SGDwikiBot: Automated import of articles

2009-05-15T21:05:11Z

Automated import of articles

SGDwikiBot: Automated import of articles

2009-03-31T21:05:12Z

Automated import of articles

SGDwikiBot: Automated import of articles

2009-01-16T21:05:13Z

Automated import of articles

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YEL034W:''' Translation elongation factor eIF-5A that may function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification<ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000144853'>Henderson A and Hershey JW (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(16):6415-9 {{SGDpaper|S000144853}} PMID 21451136</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 {{SGDpaper|S000130229}} PMID 19424157</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
+'''Description of YEL034W:''' Translation elongation factor eIF-5A; may function in translation initiation; structural homolog of bacterial EF-P; undergoes an essential hypusination modification; HYP2 has a paralog, ANB1, that arose from the whole genome duplication<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000144853'>Henderson A and Hershey JW (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(16):6415-9 {{SGDpaper|S000144853}} PMID 21451136</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 {{SGDpaper|S000130229}} PMID 19424157</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
   {{SGDpaper|S000117998}} PMID 16914118</ref>
 <br>

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000760 YEL034W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000760 YEL034W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''HYP2 ''

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YEL034W:''' Translation elongation factor eIF-5A that may function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification<ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000144853'>Henderson A and Hershey JW (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A () {{SGDpaper|S000144853}} PMID 21451136</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 {{SGDpaper|S000130229}} PMID 19424157</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
+'''Description of YEL034W:''' Translation elongation factor eIF-5A that may function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification<ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000144853'>Henderson A and Hershey JW (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(16):6415-9 {{SGDpaper|S000144853}} PMID 21451136</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 {{SGDpaper|S000130229}} PMID 19424157</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
   {{SGDpaper|S000117998}} PMID 16914118</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YEL034W:''' Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification<ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 {{SGDpaper|S000130229}} PMID 19424157</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
+'''Description of YEL034W:''' Translation elongation factor eIF-5A that may function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification<ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000144853'>Henderson A and Hershey JW (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A () {{SGDpaper|S000144853}} PMID 21451136</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 {{SGDpaper|S000130229}} PMID 19424157</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
   {{SGDpaper|S000117998}} PMID 16914118</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YEL034W:''' Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification<ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66 {{SGDpaper|S000117998}} PMID 16914118</ref><ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21
+'''Description of YEL034W:''' Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification<ref name='S000129817'>Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 {{SGDpaper|S000129817}} PMID 19338753</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 {{SGDpaper|S000130229}} PMID 19424157</ref><ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000069868'>Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 {{SGDpaper|S000069868}} PMID 11861547</ref><ref name='S000117998'>Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
- {{SGDpaper|S000130229}} PMID 19424157</ref>
+ {{SGDpaper|S000117998}} PMID 16914118</ref>
 <br>
 <br>

@@ Line 8: / Line 8: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''HYP2 ''
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''TIF51A, eIF5A''
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''TIF51A, eIF-5A, eIF5A''
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''           || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]