YDR493W - Revision history

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002901 YDR493W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002901 YDR493W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''MZM1 ''

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 |}
 <br>
-'''Description of YDR493W:''' Mitochondrial matrix protein with a role in maintaining the labile mitochondrial zinc pool; null mutant has a respiratory growth defect and an elevated frequency of mitochondrial genome loss; overexpression causes cell cycle delay or arrest<ref name='S000133883'>Atkinson A, et al. (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem 285(25):19450-9 {{SGDpaper|S000133883}} PMID 20404342</ref><ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000126952'>Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120 {{SGDpaper|S000126952}} PMID 18617996</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
+'''Description of YDR493W:''' Protein required for assembly of the cytochrome bc(1) complex; facilitates insertion of Rip1p into the complex at a late stage of assembly; localized to the mitochondrial matrix; null mutant exhibits a respiratory growth defect and reduced mitochondrial zinc levels, which is characteristic of mutations affecting bc(1) complex assembly; conserved in metazoans<ref name='S000133883'>Atkinson A, et al. (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem 285(25):19450-9 {{SGDpaper|S000133883}} PMID 20404342</ref><ref name='S000146271'>Atkinson A, et al. (2011) The LYR protein Mzm1 functions in the insertion of the Rieske Fe/S protein in yeast mitochondria. Mol Cell Biol ()
-  {{SGDpaper|S000117178}} PMID 16823961</ref>
+  {{SGDpaper|S000146271}} PMID 21807901</ref>
 <br>
 <br>

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr IV:1436210..1436581
+|nowrap| Chr IV:1436217..1436588
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000002901

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR493W:''' Mitochondrial matrix protein with a role in maintaining the labile mitochondrial zinc pool; null mutant has a respiratory growth defect and an elevated frequency of mitochondrial genome loss; overexpression causes cell cycle delay or arrest<ref name='S000133883'>Atkinson A, et al. (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem () {{SGDpaper|S000133883}} PMID 20404342</ref><ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000126952'>Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120 {{SGDpaper|S000126952}} PMID 18617996</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
+'''Description of YDR493W:''' Mitochondrial matrix protein with a role in maintaining the labile mitochondrial zinc pool; null mutant has a respiratory growth defect and an elevated frequency of mitochondrial genome loss; overexpression causes cell cycle delay or arrest<ref name='S000133883'>Atkinson A, et al. (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem 285(25):19450-9 {{SGDpaper|S000133883}} PMID 20404342</ref><ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000126952'>Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120 {{SGDpaper|S000126952}} PMID 18617996</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
   {{SGDpaper|S000117178}} PMID 16823961</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR493W:''' Protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutant displays severe respiratory growth defect and elevated frequency of mitochondrial genome loss; detected in mitochondria in high-throughput studies<ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000126952'>Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120 {{SGDpaper|S000126952}} PMID 18617996</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
+'''Description of YDR493W:''' Mitochondrial matrix protein with a role in maintaining the labile mitochondrial zinc pool; null mutant has a respiratory growth defect and an elevated frequency of mitochondrial genome loss; overexpression causes cell cycle delay or arrest<ref name='S000133883'>Atkinson A, et al. (2010) Mzm1 influences a labile pool of mitochondrial zinc important for respiratory function. J Biol Chem () {{SGDpaper|S000133883}} PMID 20404342</ref><ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000126952'>Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120 {{SGDpaper|S000126952}} PMID 18617996</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
   {{SGDpaper|S000117178}} PMID 16823961</ref>
 <br>

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002901 YDR493W]
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||'' ''
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''MZM1 ''
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''AIM8, FMP36''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''FMP36''
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''           || ORF, Uncharacterized[[Category:ORF]][[Category:ORF, Uncharacterized]]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''           || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR493W:''' Protein of unknown function; overexpression causes a cell cycle delay or arrest; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies<ref name='S000126952'>Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120 {{SGDpaper|S000126952}} PMID 18617996</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
+'''Description of YDR493W:''' Protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutant displays severe respiratory growth defect and elevated frequency of mitochondrial genome loss; detected in mitochondria in high-throughput studies<ref name='S000129658'>Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 {{SGDpaper|S000129658}} PMID 19300474</ref><ref name='S000126952'>Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120 {{SGDpaper|S000126952}} PMID 18617996</ref><ref name='S000117178'>Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
   {{SGDpaper|S000117178}} PMID 16823961</ref>
 <br>