YDR135C - Revision history

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@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002542 YDR135C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002542 YDR135C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''YCF1 ''

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR135C:''' Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR<ref name='S000073594'>Gueldry O, et al. (2003) Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae. Eur J Biochem 270(11):2486-96 {{SGDpaper|S000073594}} PMID 12755704</ref><ref name='S000044201'>Li ZS, et al. (1996) The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem 271(11):6509-17 {{SGDpaper|S000044201}} PMID 8626454</ref><ref name='S000054860'>Li ZS, et al. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. Proc Natl Acad Sci U S A 94(1):42-7 {{SGDpaper|S000054860}} PMID 8990158</ref><ref name='S000041475'>Petrovic S, et al. (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71 {{SGDpaper|S000041475}} PMID 10790694</ref><ref name='S000056085'>Szczypka MS, et al. (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein. J Biol Chem 269(36):22853-7
+'''Description of YDR135C:''' Vacuolar glutathione S-conjugate transporter; member of the ATP-binding cassette family; has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin, selenodigluthatione, and oxidized glutathione; similar to human cystic fibrosis protein CFTR<ref name='S000073594'>Gueldry O, et al. (2003) Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae. Eur J Biochem 270(11):2486-96 {{SGDpaper|S000073594}} PMID 12755704</ref><ref name='S000146592'>Lazard M, et al. (2011) Selenodiglutathione uptake by the Saccharomyces cerevisiae vacuolar ABC-transporter Ycf1p.LID - 10.1111/j.1742-4658.2011.08318.x [doi] FEBS J () {{SGDpaper|S000146592}} PMID 21880115</ref><ref name='S000044201'>Li ZS, et al. (1996) The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem 271(11):6509-17 {{SGDpaper|S000044201}} PMID 8626454</ref><ref name='S000054860'>Li ZS, et al. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. Proc Natl Acad Sci U S A 94(1):42-7 {{SGDpaper|S000054860}} PMID 8990158</ref><ref name='S000041475'>Petrovic S, et al. (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71 {{SGDpaper|S000041475}} PMID 10790694</ref><ref name='S000056085'>Szczypka MS, et al. (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein. J Biol Chem 269(36):22853-7
   {{SGDpaper|S000056085}} PMID 7521334</ref>
 <br>

@@ Line 13: / Line 13: @@
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr IV:727549..723002
+|nowrap| Chr IV:727551..723004
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000002542

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR135C:''' Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR<ref name='S000041475'>Petrovic S, et al. (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71 {{SGDpaper|S000041475}} PMID 10790694</ref><ref name='S000044201'>Li ZS, et al. (1996) The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem 271(11):6509-17 {{SGDpaper|S000044201}} PMID 8626454</ref><ref name='S000054860'>Li ZS, et al. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. Proc Natl Acad Sci U S A 94(1):42-7 {{SGDpaper|S000054860}} PMID 8990158</ref><ref name='S000056085'>Szczypka MS, et al. (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein. J Biol Chem 269(36):22853-7 {{SGDpaper|S000056085}} PMID 7521334</ref><ref name='S000073594'>Gueldry O, et al. (2003) Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae. Eur J Biochem 270(11):2486-96
+'''Description of YDR135C:''' Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR<ref name='S000073594'>Gueldry O, et al. (2003) Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae. Eur J Biochem 270(11):2486-96 {{SGDpaper|S000073594}} PMID 12755704</ref><ref name='S000044201'>Li ZS, et al. (1996) The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem 271(11):6509-17 {{SGDpaper|S000044201}} PMID 8626454</ref><ref name='S000054860'>Li ZS, et al. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. Proc Natl Acad Sci U S A 94(1):42-7 {{SGDpaper|S000054860}} PMID 8990158</ref><ref name='S000041475'>Petrovic S, et al. (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71 {{SGDpaper|S000041475}} PMID 10790694</ref><ref name='S000056085'>Szczypka MS, et al. (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein. J Biol Chem 269(36):22853-7
-  {{SGDpaper|S000073594}} PMID 12755704</ref>
+  {{SGDpaper|S000056085}} PMID 7521334</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR135C:''' Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR<ref name='S000073594'>Gueldry O, et al. (2003) Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae. Eur J Biochem 270(11):2486-96 {{SGDpaper|S000073594}} PMID 12755704</ref><ref name='S000056085'>Szczypka MS, et al. (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein. J Biol Chem 269(36):22853-7 {{SGDpaper|S000056085}} PMID 7521334</ref><ref name='S000054860'>Li ZS, et al. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. Proc Natl Acad Sci U S A 94(1):42-7 {{SGDpaper|S000054860}} PMID 8990158</ref><ref name='S000044201'>Li ZS, et al. (1996) The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem 271(11):6509-17 {{SGDpaper|S000044201}} PMID 8626454</ref><ref name='S000041475'>Petrovic S, et al. (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71
+'''Description of YDR135C:''' Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR<ref name='S000041475'>Petrovic S, et al. (2000) The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae. Yeast 16(6):561-71 {{SGDpaper|S000041475}} PMID 10790694</ref><ref name='S000044201'>Li ZS, et al. (1996) The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem 271(11):6509-17 {{SGDpaper|S000044201}} PMID 8626454</ref><ref name='S000054860'>Li ZS, et al. (1997) A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. Proc Natl Acad Sci U S A 94(1):42-7 {{SGDpaper|S000054860}} PMID 8990158</ref><ref name='S000056085'>Szczypka MS, et al. (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein. J Biol Chem 269(36):22853-7 {{SGDpaper|S000056085}} PMID 7521334</ref><ref name='S000073594'>Gueldry O, et al. (2003) Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae. Eur J Biochem 270(11):2486-96
-  {{SGDpaper|S000041475}} PMID 10790694</ref>
+  {{SGDpaper|S000073594}} PMID 12755704</ref>
 <br>
 <br>

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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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