YDR121W - Revision history

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-'''Description of YDR121W:''' Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex; involved in both chromosomal DNA replication and inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon<ref name='S000141383'>Aksenova A, et al. (2010) Mismatch Repair-Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of DNA Polymerase epsilon. PLoS Genet 6(11):e1001209 {{SGDpaper|S000141383}} PMID 21124948</ref><ref name='S000050160'>Dua R, et al. (2000) Subunit interactions within the Saccharomyces cerevisiae DNA polymerase epsilon (pol epsilon ) complex. Demonstration of a dimeric pol epsilon. J Biol Chem 275(37):28816-25 {{SGDpaper|S000050160}} PMID 10878005</ref><ref name='S000075426'>Iida T and Araki H (2004) Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 24(1):217-27 {{SGDpaper|S000075426}} PMID 14673157</ref><ref name='S000054633'>Li Y, et al. (2000) Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem 275(30):23247-52 {{SGDpaper|S000054633}} PMID 10801849</ref><ref name='S000056444'>Ohya T, et al. (2000) Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Nucleic Acids Res 28(20):3846-52
+'''Description of YDR121W:''' Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex; involved in both chromosomal DNA replication and inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon; interacts with extranucleosomal DNA and acts as anchor point for ISW2 complex that retains its position on DNA during nucleosome mobilization<ref name='S000141383'>Aksenova A, et al. (2010) Mismatch Repair-Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of DNA Polymerase epsilon. PLoS Genet 6(11):e1001209 {{SGDpaper|S000141383}} PMID 21124948</ref><ref name='S000122597'>Dang W, et al. (2007) The Dpb4 Subunit of ISW2 Is Anchored to Extranucleosomal DNA. J Biol Chem 282(27):19418-25 {{SGDpaper|S000122597}} PMID 17491017</ref><ref name='S000050160'>Dua R, et al. (2000) Subunit interactions within the Saccharomyces cerevisiae DNA polymerase epsilon (pol epsilon ) complex. Demonstration of a dimeric pol epsilon. J Biol Chem 275(37):28816-25 {{SGDpaper|S000050160}} PMID 10878005</ref><ref name='S000075426'>Iida T and Araki H (2004) Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 24(1):217-27 {{SGDpaper|S000075426}} PMID 14673157</ref><ref name='S000054633'>Li Y, et al. (2000) Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem 275(30):23247-52 {{SGDpaper|S000054633}} PMID 10801849</ref><ref name='S000056444'>Ohya T, et al. (2000) Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Nucleic Acids Res 28(20):3846-52
   {{SGDpaper|S000056444}} PMID 11024162</ref>
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-'''Description of YDR121W:''' Shared subunit of DNA polymerase (II) epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing<ref name='S000050160'>Dua R, et al. (2000) Subunit interactions within the Saccharomyces cerevisiae DNA polymerase epsilon (pol epsilon ) complex. Demonstration of a dimeric pol epsilon. J Biol Chem 275(37):28816-25 {{SGDpaper|S000050160}} PMID 10878005</ref><ref name='S000075426'>Iida T and Araki H (2004) Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 24(1):217-27 {{SGDpaper|S000075426}} PMID 14673157</ref><ref name='S000054633'>Li Y, et al. (2000) Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem 275(30):23247-52 {{SGDpaper|S000054633}} PMID 10801849</ref><ref name='S000056444'>Ohya T, et al. (2000) Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Nucleic Acids Res 28(20):3846-52
+'''Description of YDR121W:''' Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex; involved in both chromosomal DNA replication and inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon<ref name='S000141383'>Aksenova A, et al. (2010) Mismatch Repair-Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of DNA Polymerase epsilon. PLoS Genet 6(11):e1001209 {{SGDpaper|S000141383}} PMID 21124948</ref><ref name='S000050160'>Dua R, et al. (2000) Subunit interactions within the Saccharomyces cerevisiae DNA polymerase epsilon (pol epsilon ) complex. Demonstration of a dimeric pol epsilon. J Biol Chem 275(37):28816-25 {{SGDpaper|S000050160}} PMID 10878005</ref><ref name='S000075426'>Iida T and Araki H (2004) Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 24(1):217-27 {{SGDpaper|S000075426}} PMID 14673157</ref><ref name='S000054633'>Li Y, et al. (2000) Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem 275(30):23247-52 {{SGDpaper|S000054633}} PMID 10801849</ref><ref name='S000056444'>Ohya T, et al. (2000) Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Nucleic Acids Res 28(20):3846-52
   {{SGDpaper|S000056444}} PMID 11024162</ref>
 <br>

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002528 YDR121W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002528 YDR121W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''DPB4 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr IV:693583..694173
+|nowrap| Chr IV:693585..694175
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000002528

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR121W:''' Shared subunit of DNA polymerase (II) epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing<ref name='S000050160'>Dua R, et al. (2000) Subunit interactions within the Saccharomyces cerevisiae DNA polymerase epsilon (pol epsilon ) complex. Demonstration of a dimeric pol epsilon. J Biol Chem 275(37):28816-25 {{SGDpaper|S000050160}} PMID 10878005</ref><ref name='S000054633'>Li Y, et al. (2000) Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem 275(30):23247-52 {{SGDpaper|S000054633}} PMID 10801849</ref><ref name='S000056444'>Ohya T, et al. (2000) Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Nucleic Acids Res 28(20):3846-52 {{SGDpaper|S000056444}} PMID 11024162</ref><ref name='S000075426'>Iida T and Araki H (2004) Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 24(1):217-27
+'''Description of YDR121W:''' Shared subunit of DNA polymerase (II) epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing<ref name='S000050160'>Dua R, et al. (2000) Subunit interactions within the Saccharomyces cerevisiae DNA polymerase epsilon (pol epsilon ) complex. Demonstration of a dimeric pol epsilon. J Biol Chem 275(37):28816-25 {{SGDpaper|S000050160}} PMID 10878005</ref><ref name='S000075426'>Iida T and Araki H (2004) Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Mol Cell Biol 24(1):217-27 {{SGDpaper|S000075426}} PMID 14673157</ref><ref name='S000054633'>Li Y, et al. (2000) Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. J Biol Chem 275(30):23247-52 {{SGDpaper|S000054633}} PMID 10801849</ref><ref name='S000056444'>Ohya T, et al. (2000) Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Nucleic Acids Res 28(20):3846-52
- {{SGDpaper|S000075426}} PMID 14673157</ref>
+ {{SGDpaper|S000056444}} PMID 11024162</ref>
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