YDR081C - Revision history

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@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR081C:''' Putative transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions<ref name='S000050008'>Hohmann S (1993) Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):657-66 {{SGDpaper|S000050008}} PMID 8264540</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000117265'>Mojzita D and Hohmann S (2006) Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Mol Genet Genomics 276(2):147-61 {{SGDpaper|S000117265}} PMID 16850348</ref><ref name='S000128371'>Nosaka K, et al. (2008) Thiamin-dependent transactivation activity of PDC2 in Saccharomyces cerevisiae. FEBS Lett 582(29):3991-6 {{SGDpaper|S000128371}} PMID 19013460</ref><ref name='S000147201'>Raghuram V, et al. (1994) PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor J Genet 73():17-32 {{SGDpaper|S000147201}} PMID </ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
+'''Description of YDR081C:''' Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions<ref name='S000050008'>Hohmann S (1993) Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):657-66 {{SGDpaper|S000050008}} PMID 8264540</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000117265'>Mojzita D and Hohmann S (2006) Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Mol Genet Genomics 276(2):147-61 {{SGDpaper|S000117265}} PMID 16850348</ref><ref name='S000128371'>Nosaka K, et al. (2008) Thiamin-dependent transactivation activity of PDC2 in Saccharomyces cerevisiae. FEBS Lett 582(29):3991-6 {{SGDpaper|S000128371}} PMID 19013460</ref><ref name='S000148779'>Nosaka K, et al. (2012) Facilitated recruitment of Pdc2p, a yeast transcriptional activator, in response to thiamin starvation.LID - 10.1111/j.1574-6968.2012.02543.x [doi] FEMS Microbiol Lett () {{SGDpaper|S000148779}} PMID 22404710</ref><ref name='S000147201'>Raghuram V, et al. (1994) PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor J Genet 73():17-32 {{SGDpaper|S000147201}} PMID </ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
   {{SGDpaper|S000042760}} PMID 9055069</ref>
 <br>

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002488 YDR081C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002488 YDR081C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''PDC2 ''

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR081C:''' Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes<ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000055265'>Kaiser B, et al. (1999) Identification of a gene encoding the pyruvate decarboxylase gene regulator CaPdc2p from Candida albicans. Yeast 15(7):585-91 {{SGDpaper|S000055265}} PMID 10341421</ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
+'''Description of YDR081C:''' Putative transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions<ref name='S000050008'>Hohmann S (1993) Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):657-66 {{SGDpaper|S000050008}} PMID 8264540</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000117265'>Mojzita D and Hohmann S (2006) Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Mol Genet Genomics 276(2):147-61 {{SGDpaper|S000117265}} PMID 16850348</ref><ref name='S000128371'>Nosaka K, et al. (2008) Thiamin-dependent transactivation activity of PDC2 in Saccharomyces cerevisiae. FEBS Lett 582(29):3991-6 {{SGDpaper|S000128371}} PMID 19013460</ref><ref name='S000147201'>Raghuram V, et al. (1994) PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor J Genet 73():17-32 {{SGDpaper|S000147201}} PMID </ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
   {{SGDpaper|S000042760}} PMID 9055069</ref>
 <br>

@@ Line 13: / Line 13: @@
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr IV:610079..607302
+|nowrap| Chr IV:610081..607304
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000002488

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDR081C:''' Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes<ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94 {{SGDpaper|S000042760}} PMID 9055069</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000055265'>Kaiser B, et al. (1999) Identification of a gene encoding the pyruvate decarboxylase gene regulator CaPdc2p from Candida albicans. Yeast 15(7):585-91
+'''Description of YDR081C:''' Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes<ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000055265'>Kaiser B, et al. (1999) Identification of a gene encoding the pyruvate decarboxylase gene regulator CaPdc2p from Candida albicans. Yeast 15(7):585-91 {{SGDpaper|S000055265}} PMID 10341421</ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
-  {{SGDpaper|S000055265}} PMID 10341421</ref>
+  {{SGDpaper|S000042760}} PMID 9055069</ref>
 <br>
 <br>

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDR081C YDR081C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002488 YDR081C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''PDC2 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr IV:610078..607301
 |}
 <br>
-'''Description of {{PAGENAME}}:''' Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes<ref name='S000055265'>Kaiser B, et al. (1999) Identification of a gene encoding the pyruvate decarboxylase gene regulator CaPdc2p from Candida albicans. Yeast 15(7):585-91 {{SGDpaper|S000055265}} PMID 10341421</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
+'''Description of YDR081C:''' Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes<ref name='S000055265'>Kaiser B, et al. (1999) Identification of a gene encoding the pyruvate decarboxylase gene regulator CaPdc2p from Candida albicans. Yeast 15(7):585-91 {{SGDpaper|S000055265}} PMID 10341421</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
   {{SGDpaper|S000042760}} PMID 9055069</ref>
 <br>
@@ Line 37: / Line 39: @@
 J Biol Chem 278(5):3265-74</ref>
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