YDL140C - Revision history

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Galicola: /* Community Commentary */

2008-04-15T08:06:06Z

‎Community Commentary

Galicola: /* References */

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‎References

Galicola: /* References */

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‎References

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002299 YDL140C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002299 YDL140C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''RPO21 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr IV:210562..205361
+|nowrap| Chr IV:210561..205360
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000002299

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDL140C:''' RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime<ref name='S000057661'>Archambault J and Friesen JD (1993) Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev 57(3):703-24 {{SGDpaper|S000057661}} PMID 8246845</ref><ref name='S000058793'>Cramer P, et al. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288(5466):640-9 {{SGDpaper|S000058793}} PMID 10784442</ref><ref name='S000058335'>Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503 {{SGDpaper|S000058335}} PMID 9618449</ref><ref name='S000069428'>Proudfoot N (2000) Connecting transcription to messenger RNA processing. Trends Biochem Sci 25(6):290-3 {{SGDpaper|S000069428}} PMID 10838569</ref><ref name='S000080886'>Cramer P (2002) Multisubunit RNA polymerases. Curr Opin Struct Biol 12(1):89-97 {{SGDpaper|S000080886}} PMID 11839495</ref><ref name='S000074163'>Geiduschek EP and Kassavetis GA (2001) The RNA polymerase III transcription apparatus. J Mol Biol 310(1):1-26
+'''Description of YDL140C:''' RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime<ref name='S000057661'>Archambault J and Friesen JD (1993) Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev 57(3):703-24 {{SGDpaper|S000057661}} PMID 8246845</ref><ref name='S000080886'>Cramer P (2002) Multisubunit RNA polymerases. Curr Opin Struct Biol 12(1):89-97 {{SGDpaper|S000080886}} PMID 11839495</ref><ref name='S000058793'>Cramer P, et al. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288(5466):640-9 {{SGDpaper|S000058793}} PMID 10784442</ref><ref name='S000074163'>Geiduschek EP and Kassavetis GA (2001) The RNA polymerase III transcription apparatus. J Mol Biol 310(1):1-26 {{SGDpaper|S000074163}} PMID 11419933</ref><ref name='S000058335'>Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503 {{SGDpaper|S000058335}} PMID 9618449</ref><ref name='S000069428'>Proudfoot N (2000) Connecting transcription to messenger RNA processing. Trends Biochem Sci 25(6):290-3
- {{SGDpaper|S000074163}} PMID 11419933</ref>
+ {{SGDpaper|S000069428}} PMID 10838569</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDL140C:''' RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime<ref name='S000080886'>Cramer P (2002) Multisubunit RNA polymerases. Curr Opin Struct Biol 12(1):89-97 {{SGDpaper|S000080886}} PMID 11839495</ref><ref name='S000074163'>Geiduschek EP and Kassavetis GA (2001) The RNA polymerase III transcription apparatus. J Mol Biol 310(1):1-26 {{SGDpaper|S000074163}} PMID 11419933</ref><ref name='S000069428'>Proudfoot N (2000) Connecting transcription to messenger RNA processing. Trends Biochem Sci 25(6):290-3 {{SGDpaper|S000069428}} PMID 10838569</ref><ref name='S000058793'>Cramer P, et al. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288(5466):640-9 {{SGDpaper|S000058793}} PMID 10784442</ref><ref name='S000058335'>Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503 {{SGDpaper|S000058335}} PMID 9618449</ref><ref name='S000057661'>Archambault J and Friesen JD (1993) Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev 57(3):703-24
+'''Description of YDL140C:''' RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime<ref name='S000057661'>Archambault J and Friesen JD (1993) Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev 57(3):703-24 {{SGDpaper|S000057661}} PMID 8246845</ref><ref name='S000058793'>Cramer P, et al. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288(5466):640-9 {{SGDpaper|S000058793}} PMID 10784442</ref><ref name='S000058335'>Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503 {{SGDpaper|S000058335}} PMID 9618449</ref><ref name='S000069428'>Proudfoot N (2000) Connecting transcription to messenger RNA processing. Trends Biochem Sci 25(6):290-3 {{SGDpaper|S000069428}} PMID 10838569</ref><ref name='S000080886'>Cramer P (2002) Multisubunit RNA polymerases. Curr Opin Struct Biol 12(1):89-97 {{SGDpaper|S000080886}} PMID 11839495</ref><ref name='S000074163'>Geiduschek EP and Kassavetis GA (2001) The RNA polymerase III transcription apparatus. J Mol Biol 310(1):1-26
-  {{SGDpaper|S000057661}} PMID 8246845</ref>
+  {{SGDpaper|S000074163}} PMID 11419933</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YDL140C:''' RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime<ref name='S000057661'>Archambault J and Friesen JD (1993) Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev 57(3):703-24 {{SGDpaper|S000057661}} PMID 8246845</ref><ref name='S000058335'>Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503 {{SGDpaper|S000058335}} PMID 9618449</ref><ref name='S000058793'>Cramer P, et al. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288(5466):640-9 {{SGDpaper|S000058793}} PMID 10784442</ref><ref name='S000069428'>Proudfoot N (2000) Connecting transcription to messenger RNA processing. Trends Biochem Sci 25(6):290-3 {{SGDpaper|S000069428}} PMID 10838569</ref><ref name='S000074163'>Geiduschek EP and Kassavetis GA (2001) The RNA polymerase III transcription apparatus. J Mol Biol 310(1):1-26 {{SGDpaper|S000074163}} PMID 11419933</ref><ref name='S000080886'>Cramer P (2002) Multisubunit RNA polymerases. Curr Opin Struct Biol 12(1):89-97
+'''Description of YDL140C:''' RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime<ref name='S000080886'>Cramer P (2002) Multisubunit RNA polymerases. Curr Opin Struct Biol 12(1):89-97 {{SGDpaper|S000080886}} PMID 11839495</ref><ref name='S000074163'>Geiduschek EP and Kassavetis GA (2001) The RNA polymerase III transcription apparatus. J Mol Biol 310(1):1-26 {{SGDpaper|S000074163}} PMID 11419933</ref><ref name='S000069428'>Proudfoot N (2000) Connecting transcription to messenger RNA processing. Trends Biochem Sci 25(6):290-3 {{SGDpaper|S000069428}} PMID 10838569</ref><ref name='S000058793'>Cramer P, et al. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288(5466):640-9 {{SGDpaper|S000058793}} PMID 10784442</ref><ref name='S000058335'>Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503 {{SGDpaper|S000058335}} PMID 9618449</ref><ref name='S000057661'>Archambault J and Friesen JD (1993) Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev 57(3):703-24
-  {{SGDpaper|S000080886}} PMID 11839495</ref>
+  {{SGDpaper|S000057661}} PMID 8246845</ref>
 <br>
 <br>

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← Older revision		Revision as of 08:05, 15 April 2008
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−
−	Rpb1-1 mutation: this is a ts mutant which does not transcribe at the restrictive temperature. According to Scafe, S., Martin, C., Nonet, M., Podos, S., Okamura, S. and Young, R. (MCB 1990 vol. 10(3):1270-1275) this mutation is G->A at base 4622 (base 1 is A of ATG). However, according the Nedea, EC., Markov, D., Naryshkina, T. and Severinov, K. (J. Bact. 1999 Vol 181(8):2663-2665) the rpb1-1 mutation is equivalent to a parallel ts mutation in the E. coli RNA pol, in a conserved Glycine. According to their article, the rpb1-1 mutation is in this conserved Gly (aa 1437, or base 4310) and not Gly 1541 (base 4622 according to R. Young).
−	~~After sequencing two rpb1-1 mutants in our posession, we agree with Severinov, that the G->A mutation is at base 4310 and NOT in base 4622.~~