YCR094W - Revision history

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-'''Description of YCR094W:''' Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p<ref name='S000130257'>Lenoir G, et al. (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67 {{SGDpaper|S000130257}} PMID 19411703</ref><ref name='S000072635'>Misu K, et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol Biol Cell 14(2):730-47 {{SGDpaper|S000072635}} PMID 12589066</ref><ref name='S000059546'>Radji M, et al. (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205 {{SGDpaper|S000059546}} PMID 11180453</ref><ref name='S000076777'>Saito K, et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32
+'''Description of YCR094W:''' Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication<ref name='S000113653'>Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 {{SGDpaper|S000113653}} PMID 16169922</ref><ref name='S000130257'>Lenoir G, et al. (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67 {{SGDpaper|S000130257}} PMID 19411703</ref><ref name='S000072635'>Misu K, et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol Biol Cell 14(2):730-47 {{SGDpaper|S000072635}} PMID 12589066</ref><ref name='S000059546'>Radji M, et al. (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205 {{SGDpaper|S000059546}} PMID 11180453</ref><ref name='S000076777'>Saito K, et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32
   {{SGDpaper|S000076777}} PMID 15090616</ref>
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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000690 YCR094W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000690 YCR094W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''CDC50 ''

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr III:286759..287934
+|nowrap| Chr III:286762..287937
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000000690

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCR094W:''' Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p<ref name='S000059546'>Radji M, et al. (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205 {{SGDpaper|S000059546}} PMID 11180453</ref><ref name='S000076777'>Saito K, et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32 {{SGDpaper|S000076777}} PMID 15090616</ref><ref name='S000072635'>Misu K, et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol Biol Cell 14(2):730-47 {{SGDpaper|S000072635}} PMID 12589066</ref><ref name='S000130257'>Lenoir G, et al. (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67
+'''Description of YCR094W:''' Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p<ref name='S000130257'>Lenoir G, et al. (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67 {{SGDpaper|S000130257}} PMID 19411703</ref><ref name='S000072635'>Misu K, et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol Biol Cell 14(2):730-47 {{SGDpaper|S000072635}} PMID 12589066</ref><ref name='S000059546'>Radji M, et al. (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205 {{SGDpaper|S000059546}} PMID 11180453</ref><ref name='S000076777'>Saito K, et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32
-  {{SGDpaper|S000130257}} PMID 19411703</ref>
+  {{SGDpaper|S000076777}} PMID 15090616</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCR094W:''' Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p<ref name='S000059546'>Radji M, et al. (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205 {{SGDpaper|S000059546}} PMID 11180453</ref><ref name='S000076777'>Saito K, et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32 {{SGDpaper|S000076777}} PMID 15090616</ref><ref name='S000072635'>Misu K, et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol Biol Cell 14(2):730-47 {{SGDpaper|S000072635}} PMID 12589066</ref><ref name='S000130257'>Lenoir G, et al. (2009) Cdc50p Plays a Vital Role in the ATPase Reaction Cycle of the Putative Aminophospholipid Transporter DRS2P. J Biol Chem
+'''Description of YCR094W:''' Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p<ref name='S000059546'>Radji M, et al. (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205 {{SGDpaper|S000059546}} PMID 11180453</ref><ref name='S000076777'>Saito K, et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32 {{SGDpaper|S000076777}} PMID 15090616</ref><ref name='S000072635'>Misu K, et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol Biol Cell 14(2):730-47 {{SGDpaper|S000072635}} PMID 12589066</ref><ref name='S000130257'>Lenoir G, et al. (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67
   {{SGDpaper|S000130257}} PMID 19411703</ref>
 <br>