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{{PageTop}}
{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YCL067C YCL067C]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''HMLALPHA2 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''ALPHA2''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, silenced_gene,Verified[[Category:ORF]][[Category:ORF, silenced_gene,Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr III:13018..12386
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000058493}} PMID </ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82
{{SGDpaper|S000044255}} PMID 3127056</ref>
 
 
 
 

__TOC__
==Community Commentary==
{{CommentaryHelp}}

==References==

{{RefHelp}}

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82 {{SGDpaper|S000044255}} PMID 3127056</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
+'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82 {{SGDpaper|S000044255}} PMID 3127056</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000058493}} PMID </ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7
-  {{SGDpaper|S000058493}} PMID </ref>
+  {{SGDpaper|S000051804}} PMID 10568744</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000058493}} PMID </ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82
+'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82 {{SGDpaper|S000044255}} PMID 3127056</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
-  {{SGDpaper|S000044255}} PMID 3127056</ref>
+  {{SGDpaper|S000058493}} PMID </ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82 {{SGDpaper|S000044255}} PMID 3127056</ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
+'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000058493}} PMID </ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82
-  {{SGDpaper|S000058493}} PMID </ref>
+  {{SGDpaper|S000044255}} PMID 3127056</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000058493}} PMID </ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82
+'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82 {{SGDpaper|S000044255}} PMID 3127056</ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
-  {{SGDpaper|S000044255}} PMID 3127056</ref>
+  {{SGDpaper|S000058493}} PMID </ref>
 <br>
 <br>

← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
		+	<!--
		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000572 YCL067C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000572 YCL067C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''HMLALPHA2 ''

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YCL067C YCL067C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000572 YCL067C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''HMLALPHA2 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr III:13018..12386
 |}
 <br>
-'''Description of {{PAGENAME}}:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000058493}} PMID </ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82
+'''Description of YCL067C:''' Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression<ref name='S000058493'>Herskowitz I, et al. (1992) Mating-type determination and mating-type interconversion in Saccharomyces cerevisiae. Pp. 583-656 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000058493}} PMID </ref><ref name='S000056867'>Herskowitz I (1989) A regulatory hierarchy for cell specialization in yeast. Nature 342(6251):749-57 {{SGDpaper|S000056867}} PMID 2513489</ref><ref name='S000055738'>Smith DL and Johnson AD (1992) A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an alpha 2 dimer. Cell 68(1):133-42 {{SGDpaper|S000055738}} PMID 1732062</ref><ref name='S000054505'>Goutte C and Johnson AD (1993) Yeast a1 and alpha 2 homeodomain proteins form a DNA-binding activity with properties distinct from those of either protein. J Mol Biol 233(3):359-71 {{SGDpaper|S000054505}} PMID 8411150</ref><ref name='S000051804'>Zhong H, et al. (1999) Identification of target sites of the alpha2-Mcm1 repressor complex in the yeast genome. Genome Res 9(11):1040-7 {{SGDpaper|S000051804}} PMID 10568744</ref><ref name='S000050461'>Goutte C and Johnson AD (1994) Recognition of a DNA operator by a dimer composed of two different homeodomain proteins. EMBO J 13(6):1434-42 {{SGDpaper|S000050461}} PMID 7907979</ref><ref name='S000044904'>Vershon AK and Johnson AD (1993) A short, disordered protein region mediates interactions between the homeodomain of the yeast alpha 2 protein and the MCM1 protein. Cell 72(1):105-12 {{SGDpaper|S000044904}} PMID 8422672</ref><ref name='S000044339'>Murphy MR, et al. (1993) DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res 21(14):3295-300 {{SGDpaper|S000044339}} PMID 8341604</ref><ref name='S000044255'>Goutte C and Johnson AD (1988) a1 protein alters the DNA binding specificity of alpha 2 repressor. Cell 52(6):875-82
   {{SGDpaper|S000044255}} PMID 3127056</ref>
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 J Biol Chem 278(5):3265-74</ref>
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr III:13018..12386
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 ==Community Commentary==
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 ==References==
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