YCL017C - Revision history

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{{PageTop}}
{|{{Prettytable}} align = 'right' width = '200px'
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YCL017C YCL017C]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NFS1 ''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''SPL1''
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
|-
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr III:94270..92777
|-
|colspan = '3'|{{Don'tEditThisBox}}
|}
 
'''Description of {{PAGENAME}}:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9
{{SGDpaper|S000040793}} PMID 10406803</ref>
 
 
 
 

__TOC__
==Community Commentary==
{{CommentaryHelp}}

==References==

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 |}
 <br>
-'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9 {{SGDpaper|S000040793}} PMID 10406803</ref><ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8
+'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis and in thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9 {{SGDpaper|S000040793}} PMID 10406803</ref><ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8
   {{SGDpaper|S000076186}} PMID 14722066</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9 {{SGDpaper|S000040793}} PMID 10406803</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15
+'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9 {{SGDpaper|S000040793}} PMID 10406803</ref><ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8
-  {{SGDpaper|S000076996}} PMID 15220327</ref>
+  {{SGDpaper|S000076186}} PMID 14722066</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9
+'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9 {{SGDpaper|S000040793}} PMID 10406803</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15
-  {{SGDpaper|S000040793}} PMID 10406803</ref>
+  {{SGDpaper|S000076996}} PMID 15220327</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9 {{SGDpaper|S000040793}} PMID 10406803</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15
+'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9
-  {{SGDpaper|S000076996}} PMID 15220327</ref>
+  {{SGDpaper|S000040793}} PMID 10406803</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9
+'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9 {{SGDpaper|S000040793}} PMID 10406803</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15
-  {{SGDpaper|S000040793}} PMID 10406803</ref>
+  {{SGDpaper|S000076996}} PMID 15220327</ref>
 <br>
 <br>

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000522 YCL017C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000522 YCL017C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''NFS1 ''

@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YCL017C YCL017C]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000522 YCL017C]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''NFS1 ''
@@ Line 14: / Line 14: @@
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr III:94270..92777
 |}
 <br>
-'''Description of {{PAGENAME}}:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9
+'''Description of YCL017C:''' Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria<ref name='S000076996'>Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 {{SGDpaper|S000076996}} PMID 15220327</ref><ref name='S000076186'>Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 {{SGDpaper|S000076186}} PMID 14722066</ref><ref name='S000040793'>Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9
   {{SGDpaper|S000040793}} PMID 10406803</ref>
 <br>
@@ Line 37: / Line 39: @@
 J Biol Chem 278(5):3265-74</ref>
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← Older revision		Revision as of 20:02, 21 February 2007
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		+	<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
		+	<!--
		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 |nowrap| Chr III:94270..92777
 |}
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+<br>
 __TOC__
 ==Community Commentary==
 {{CommentaryHelp}}
 ==References==
 <!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 {{RefHelp}}