YBL020W - Revision history

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@@ Line 4: / Line 4: @@
 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000116 YBL020W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000116 YBL020W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''RFT1 ''

@@ Line 13: / Line 13: @@
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr II:182404..184128
+|nowrap| Chr II:182401..184125
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000000116

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YBL020W:''' Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein<ref name='S000046279'>Koerte A, et al. (1995) Suppression of the yeast mutation rft1-1 by human p53. J Biol Chem 270(38):22556-64 {{SGDpaper|S000046279}} PMID 7673248</ref><ref name='S000069444'>Helenius J, et al. (2002) Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature 415(6870):447-50 {{SGDpaper|S000069444}} PMID 11807558</ref><ref name='S000126850'>Sanyal S, et al. (2008) Distinct flippases translocate glycerophospholipids and oligosaccharide diphosphate dolichols across the endoplasmic reticulum. Biochemistry 47(30):7937-46 {{SGDpaper|S000126850}} PMID 18597486</ref><ref name='S000130527'>Rush JS, et al. (2009) Suppression of Rft1 Expression Does Not Impair the Transbilayer Movement of Man5GlcNAc2-P-P-Dolichol in Sealed Microsomes from Yeast. J Biol Chem 284(30):19835-42 {{SGDpaper|S000130527}} PMID 19494107</ref><ref name='S000127251'>Frank CG, et al. (2008) Does Rft1 flip an N-glycan lipid precursor? Nature 454(7204):E3-4; discussion E4-5
+'''Description of YBL020W:''' Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein<ref name='S000127251'>Frank CG, et al. (2008) Does Rft1 flip an N-glycan lipid precursor? Nature 454(7204):E3-4; discussion E4-5 {{SGDpaper|S000127251}} PMID 18668045</ref><ref name='S000069444'>Helenius J, et al. (2002) Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature 415(6870):447-50 {{SGDpaper|S000069444}} PMID 11807558</ref><ref name='S000046279'>Koerte A, et al. (1995) Suppression of the yeast mutation rft1-1 by human p53. J Biol Chem 270(38):22556-64 {{SGDpaper|S000046279}} PMID 7673248</ref><ref name='S000130527'>Rush JS, et al. (2009) Suppression of Rft1 Expression Does Not Impair the Transbilayer Movement of Man5GlcNAc2-P-P-Dolichol in Sealed Microsomes from Yeast. J Biol Chem 284(30):19835-42 {{SGDpaper|S000130527}} PMID 19494107</ref><ref name='S000126850'>Sanyal S, et al. (2008) Distinct flippases translocate glycerophospholipids and oligosaccharide diphosphate dolichols across the endoplasmic reticulum. Biochemistry 47(30):7937-46
-  {{SGDpaper|S000127251}} PMID 18668045</ref>
+  {{SGDpaper|S000126850}} PMID 18597486</ref>
 <br>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YBL020W:''' Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein<ref name='S000046279'>Koerte A, et al. (1995) Suppression of the yeast mutation rft1-1 by human p53. J Biol Chem 270(38):22556-64 {{SGDpaper|S000046279}} PMID 7673248</ref><ref name='S000069444'>Helenius J, et al. (2002) Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature 415(6870):447-50 {{SGDpaper|S000069444}} PMID 11807558</ref><ref name='S000126850'>Sanyal S, et al. (2008) Distinct flippases translocate glycerophospholipids and oligosaccharide diphosphate dolichols across the endoplasmic reticulum. Biochemistry 47(30):7937-46 {{SGDpaper|S000126850}} PMID 18597486</ref><ref name='S000127251'>Frank CG, et al. (2008) Does Rft1 flip an N-glycan lipid precursor? Nature 454(7204):E3-4; discussion E4-5
+'''Description of YBL020W:''' Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein<ref name='S000046279'>Koerte A, et al. (1995) Suppression of the yeast mutation rft1-1 by human p53. J Biol Chem 270(38):22556-64 {{SGDpaper|S000046279}} PMID 7673248</ref><ref name='S000069444'>Helenius J, et al. (2002) Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature 415(6870):447-50 {{SGDpaper|S000069444}} PMID 11807558</ref><ref name='S000126850'>Sanyal S, et al. (2008) Distinct flippases translocate glycerophospholipids and oligosaccharide diphosphate dolichols across the endoplasmic reticulum. Biochemistry 47(30):7937-46 {{SGDpaper|S000126850}} PMID 18597486</ref><ref name='S000130527'>Rush JS, et al. (2009) Suppression of Rft1 Expression Does Not Impair the Transbilayer Movement of Man5GlcNAc2-P-P-Dolichol in Sealed Microsomes from Yeast. J Biol Chem 284(30):19835-42 {{SGDpaper|S000130527}} PMID 19494107</ref><ref name='S000127251'>Frank CG, et al. (2008) Does Rft1 flip an N-glycan lipid precursor? Nature 454(7204):E3-4; discussion E4-5
   {{SGDpaper|S000127251}} PMID 18668045</ref>
 <br>

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YBL020W:''' Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein<ref name='S000127251'>Frank CG, et al. (2008) Does Rft1 flip an N-glycan lipid precursor? Nature 454(7204):E3-4; discussion E4-5 {{SGDpaper|S000127251}} PMID 18668045</ref><ref name='S000126850'>Sanyal S, et al. (2008) Distinct flippases translocate glycerophospholipids and oligosaccharide diphosphate dolichols across the endoplasmic reticulum. Biochemistry 47(30):7937-46 {{SGDpaper|S000126850}} PMID 18597486</ref><ref name='S000069444'>Helenius J, et al. (2002) Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature 415(6870):447-50 {{SGDpaper|S000069444}} PMID 11807558</ref><ref name='S000046279'>Koerte A, et al. (1995) Suppression of the yeast mutation rft1-1 by human p53. J Biol Chem 270(38):22556-64
+'''Description of YBL020W:''' Essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein<ref name='S000046279'>Koerte A, et al. (1995) Suppression of the yeast mutation rft1-1 by human p53. J Biol Chem 270(38):22556-64 {{SGDpaper|S000046279}} PMID 7673248</ref><ref name='S000069444'>Helenius J, et al. (2002) Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature 415(6870):447-50 {{SGDpaper|S000069444}} PMID 11807558</ref><ref name='S000126850'>Sanyal S, et al. (2008) Distinct flippases translocate glycerophospholipids and oligosaccharide diphosphate dolichols across the endoplasmic reticulum. Biochemistry 47(30):7937-46 {{SGDpaper|S000126850}} PMID 18597486</ref><ref name='S000127251'>Frank CG, et al. (2008) Does Rft1 flip an N-glycan lipid precursor? Nature 454(7204):E3-4; discussion E4-5
-  {{SGDpaper|S000046279}} PMID 7673248</ref>
+  {{SGDpaper|S000127251}} PMID 18668045</ref>
 <br>
 <br>

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		+	Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
		+	<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
		+	J Biol Chem 278(5):3265-74</ref>
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