YAL002W - Revision history

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 {|{{Prettytable}} align = 'right' width = '200px'
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000002 YAL002W]
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000002 YAL002W]
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''VPS8 ''

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 |}
 <br>
-'''Description of YAL002W:''' Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif<ref name='S000048903'>Chen YJ and Stevens TH (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97 {{SGDpaper|S000048903}} PMID 8864656</ref><ref name='S000043076'>Horazdovsky BF, et al. (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15 {{SGDpaper|S000043076}} PMID 8969229</ref><ref name='S000043091'>Luo W and Chang A (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46 {{SGDpaper|S000043091}} PMID 9265642</ref><ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50
+'''Description of YAL002W:''' Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif<ref name='S000048903'>Chen YJ and Stevens TH (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97 {{SGDpaper|S000048903}} PMID 8864656</ref><ref name='S000043076'>Horazdovsky BF, et al. (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15 {{SGDpaper|S000043076}} PMID 8969229</ref><ref name='S000043091'>Luo W and Chang A (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46 {{SGDpaper|S000043091}} PMID 9265642</ref><ref name='S000131961'>Markgraf DF, et al. (2009) The CORVET Subunit Vps8 Cooperates with the Rab5 Homolog Vps21 to Induce Clustering of Late Endosomal Compartments. Mol Biol Cell 20(24):5276-89 {{SGDpaper|S000131961}} PMID 19828734</ref><ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50
   {{SGDpaper|S000122612}} PMID 17488625</ref>
 <br>

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
-|nowrap| Chr I:143709..147533
+|nowrap| Chr I:143707..147531
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''           || S000000002

@@ Line 18: / Line 18: @@
 |}
 <br>
-'''Description of YAL002W:''' Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif<ref name='S000043091'>Luo W and Chang A (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46 {{SGDpaper|S000043091}} PMID 9265642</ref><ref name='S000043076'>Horazdovsky BF, et al. (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15 {{SGDpaper|S000043076}} PMID 8969229</ref><ref name='S000048903'>Chen YJ and Stevens TH (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97 {{SGDpaper|S000048903}} PMID 8864656</ref><ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50
+'''Description of YAL002W:''' Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif<ref name='S000048903'>Chen YJ and Stevens TH (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97 {{SGDpaper|S000048903}} PMID 8864656</ref><ref name='S000043076'>Horazdovsky BF, et al. (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15 {{SGDpaper|S000043076}} PMID 8969229</ref><ref name='S000043091'>Luo W and Chang A (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46 {{SGDpaper|S000043091}} PMID 9265642</ref><ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50
   {{SGDpaper|S000122612}} PMID 17488625</ref>
 <br>

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 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''         ||''VPS8 ''
 |-
-|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''FUN15, VPT8''
+|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''           ||''FUN15, VPL8, VPT8''
 |-
 |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''           || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]