View source for Details of 2024 Reference Genome Annotation Update R64.5

The ''S. cerevisiae'' strain S288C reference genome annotation was updated. The new genome annotation is release R64.5.1, dated 2024-05-29.  Note that the underlying genome sequence itself was not altered. The chromosome sequences remain stable.

==R64.5 Annotation update summary==
This annotation update included (details in table below):
*new ORFs:
**[https://www.yeastgenome.org/locus/YDL204W-A YDL204W-A]
**[https://www.yeastgenome.org/locus/YFR035W-A YFR035W-A]
**[https://www.yeastgenome.org/locus/YGR016C-A YGR016C-A]
**[https://www.yeastgenome.org/locus/YMR106W-A YMR106W-A]
**[https://www.yeastgenome.org/locus/YNL040C-A YNL040C-A]
**[https://www.yeastgenome.org/locus/YNL155C-A YNL155C-A]
*new uORFs for existing ORFs: 
**[https://www.yeastgenome.org/locus/ATG12 ATG12/YBR217W]
**[https://www.yeastgenome.org/locus/ATG19 ATG19/YOL082W]
**[https://www.yeastgenome.org/locus/ATG5 ATG5/YPL149W]
**[https://www.yeastgenome.org/locus/ATG13 ATG13/YPR185W]
*move start downstream: [https://www.yeastgenome.org/locus/EFM4 EFM4/YIL064W]
*ORF upgraded from Dubious to Verified: [https://www.yeastgenome.org/locus/YIL059C YIL059C]

==R64.5 Annotation update details==
{| border="1" style="border-collapse:collapse; width:90%" cellpadding="3"
|-
! style="background: #D8D8D8" | Chr
! style="background: #D8D8D8" | Feature
! style="background: #D8D8D8" | Description of change
! style="background: #D8D8D8" | Reference
|-
|II
|[https://www.yeastgenome.org/locus/ATG12 ATG12/YBR217W]
|New uORF chrII:657824..657835, partially overlaps CDS
|[https://www.yeastgenome.org/reference/S000314966 Yang Y, et al. (2023)] PMID:35363116
|-
|IV
|[https://www.yeastgenome.org/locus/YDL204W-A YDL204W-A]
|New ORF chrIV:94133..94285
|[https://www.yeastgenome.org/reference/S000343589 Wacholder A, et al. (2023)] PMID:37164009
|-
|VI
|[https://www.yeastgenome.org/locus/YFR035W-A YFR035W-A]
|New ORF chrVI:226260..226550
|[https://www.yeastgenome.org/reference/S000346762 Wacholder A and Carvunis AR (2023)] PMID:38048358
|-
|VII
|[https://www.yeastgenome.org/locus/YGR016C-A YGR016C-A]
|New ORF chrVII:523353..523246
|[https://www.yeastgenome.org/reference/S000343589 Wacholder A, et al. (2023)] PMID:37164009,  
[https://www.yeastgenome.org/reference/S000346184 Chang S, et al. (2023)] PMID:37927910
|-
|IX
|[https://www.yeastgenome.org/locus/EFM4 EFM4/YIL064W]
|Move start 84 nucleotides downstream, new coordinates chrIX:242027..242716
|[https://www.yeastgenome.org/reference/S000347127 Hamey JJ, et al. (2024)] PMID:38199565
|-
|IX
|[https://www.yeastgenome.org/locus/YIL059C YIL059C]
|Change ORF qualifier from Dubious to Verified because stable translation product detected
|[https://www.yeastgenome.org/reference/S000346762 Wacholder A and Carvunis AR (2023)] PMID:38048358
|-
|XIII
|[https://www.yeastgenome.org/locus/YMR106W-A YMR106W-A]
|New ORF chrXIII:480924..481187
|[https://www.yeastgenome.org/reference/S000346762 Wacholder A and Carvunis AR (2023)] PMID:38048358
|-
|XIV
|[https://www.yeastgenome.org/locus/YNL040C-A YNL040C-A]
|New ORF chrXIV:552558..552478
|[https://www.yeastgenome.org/reference/S000343589 Wacholder A, et al. (2023)] PMID:37164009
|-
|XIV
|[https://www.yeastgenome.org/locus/YNL155C-A YNL155C-A]
|New ORF chrXIV:342135..341911
|[https://www.yeastgenome.org/reference/S000346762 Wacholder A and Carvunis AR (2023)] PMID:38048358
|-
|XV
|[https://www.yeastgenome.org/locus/ATG19 ATG19/YOL082W]
|New uORF chrXV:168632..168679
|[https://www.yeastgenome.org/reference/S000314966 Yang Y, et al. (2023)] PMID:35363116
|-
|XVI
|[https://www.yeastgenome.org/locus/ATG5 ATG5/YPL149W]
|4 new uORFs: chrXVI:271236..271277, chrXVI:271252..271302, chrXVI:271299..271307, chrXVI:271302..271307
|[https://www.yeastgenome.org/reference/S000314966 Yang Y, et al. (2023)] PMID:35363116
|-
|XVI
|[https://www.yeastgenome.org/locus/ATG13 ATG13/YPR185W]
|New uORF chrXVI:907211..907351, partially overlaps CDS
|[https://www.yeastgenome.org/reference/S000314966 Yang Y, et al. (2023)] PMID:35363116
|-
|}