YHL028W

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Systematic name YHL028W
Gene name WSC4
Aliases YFW1, YHC8
Feature type ORF, Verified
Coordinates Chr VIII:48763..50580
Primary SGDID S000001020


Description of YHL028W: ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3[1][2]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [3] [4]





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References

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  1. Mamoun CB, et al. (1999) Disruption of YHC8, a member of the TSR1 gene family, reveals its direct involvement in yeast protein translocation. J Biol Chem 274(16):11296-302 SGD PMID 10196219
  2. Zu T, et al. (2001) Mutations in WSC genes for putative stress receptors result in sensitivity to multiple stress conditions and impairment of Rlm1-dependent gene expression in Saccharomyces cerevisiae. Mol Genet Genomics 266(1):142-55 SGD PMID 11589572
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25

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