YLR115W

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Systematic name YLR115W
Gene name CFT2
Aliases YDH1
Feature type ORF, Verified
Coordinates Chr XII:377985..380564
Primary SGDID S000004105


Description of YLR115W: Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein.[1][2][3]




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References

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  1. Kyburz A, et al. (2003) The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation. Nucleic Acids Res 31(14):3936-45 SGD PMID 12853609
  2. Preker PJ, et al. (1997) A multisubunit 3' end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16(15):4727-37 SGD PMID 9303317
  3. Zhao J, et al. (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8 SGD PMID 9099738

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