YNL154C

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Systematic name YNL154C
Gene name YCK2
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:345276..343636
Primary SGDID S000005098


Description of YNL154C: Palmitoylated plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p[1][2][3][4][5][6][7][8][9]




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References

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  1. Babu P, et al. (2004) Akr1p-dependent palmitoylation of Yck2p yeast casein kinase 1 is necessary and sufficient for plasma membrane targeting. J Biol Chem 279(26):27138-47 SGD PMID 15105419
  2. Feng Y and Davis NG (2000) Akr1p and the type I casein kinases act prior to the ubiquitination step of yeast endocytosis: Akr1p is required for kinase localization to the plasma membrane. Mol Cell Biol 20(14):5350-9 SGD PMID 10866691
  3. Hicke L, et al. (1998) Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization. J Cell Biol 141(2):349-58 SGD PMID 9548714
  4. Marchal C, et al. (2000) Casein kinase I-dependent phosphorylation within a PEST sequence and ubiquitination at nearby lysines signal endocytosis of yeast uracil permease. J Biol Chem 275(31):23608-14 SGD PMID 10811641
  5. Robinson LC, et al. (1992) Yeast casein kinase I homologues: an essential gene pair. Proc Natl Acad Sci U S A 89(1):28-32 SGD PMID 1729698
  6. Robinson LC, et al. (1993) Casein kinase I-like protein kinases encoded by YCK1 and YCK2 are required for yeast morphogenesis. Mol Cell Biol 13(5):2870-81 SGD PMID 8474447
  7. Robinson LC, et al. (1999) The Yck2 yeast casein kinase 1 isoform shows cell cycle-specific localization to sites of polarized growth and is required for proper septin organization. Mol Biol Cell 10(4):1077-92 SGD PMID 10198058
  8. Roth AF, et al. (2002) The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase. J Cell Biol 159(1):23-8 SGD PMID 12370247
  9. Wang PC, et al. (1992) Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1. Mol Biol Cell 3(3):275-86 SGD PMID 1627830

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