YOR083W
(Redirected from WHI5)
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| Systematic name | YOR083W |
| Gene name | WHI5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:479533..480420 |
| Primary SGDID | S000005609 |
Description of YOR083W: Repressor of G1 transcription that binds to SCB binding factor (SBF) at SCB target promoters in early G1; phosphorylation of Whi5p by the CDK, Cln3p/Cdc28p relieves repression and promoter binding by Whi5; periodically expressed in G1[1][2][3][4]
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References
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- ↑ Costanzo M, et al. (2004) CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast. Cell 117(7):899-913 SGD PMID 15210111
- ↑ Jorgensen P, et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400 SGD PMID 12089449
- ↑ Spellman PT, et al. (1998) Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol Biol Cell 9(12):3273-97 SGD PMID 9843569
- ↑ de Bruin RA, et al. (2004) Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5. Cell 117(7):887-98 SGD PMID 15210110
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