YOR132W
(Redirected from VPT3)
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| Systematic name | YOR132W |
| Gene name | VPS17 |
| Aliases | PEP21, VPT3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:573175..574830 |
| Primary SGDID | S000005658 |
Description of YOR132W: Subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde protein transport; peripheral membrane protein that assembles onto the membrane with Vps5p to promote vesicle formation; required for recruiting the retromer complex to the endosome membranes[1][2][3][4]
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References
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- ↑ Horazdovsky BF, et al. (1997) A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor. Mol Biol Cell 8(8):1529-41 SGD PMID 9285823
- ↑ Kohrer K and Emr SD (1993) The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases. J Biol Chem 268(1):559-69 SGD PMID 8416961
- ↑ Liu TT, et al. (2012) Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23(13):2505-15 SGD PMID 22593205
- ↑ Seaman MN, et al. (1998) A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol 142(3):665-81 SGD PMID 9700157
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