YDL153C

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Systematic name YDL153C
Gene name SAS10
Aliases UTP3
Feature type ORF, Verified
Coordinates Chr IV:183018..181186
Primary SGDID S000002312


Description of YDL153C: Essential subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit; disrupts silencing when overproduced; mutant has increased aneuploidy tolerance[1][2][3]




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References

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  1. Dragon F, et al. (2002) A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature 417(6892):967-70 SGD PMID 12068309
  2. Kamakaka RT and Rine J (1998) Sir- and silencer-independent disruption of silencing in Saccharomyces by Sas10p. Genetics 149(2):903-14 SGD PMID 9611201
  3. Torres EM, et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83 SGD PMID 20850176

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