YHR077C
(Redirected from UPF2)
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| Systematic name | YHR077C |
| Gene name | NMD2 |
| Aliases | IFS1, SUA1, SUP111, UPF2 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:255756..252374 |
| Primary SGDID | S000001119 |
Description of YHR077C: Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance[1][2][3][4]
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Interactions
Two Hybrid
Two Hybrid interaction with NAM7
Yeast Two-Hybrid screen with Upf1p as bait identified several interacting proteins [3] [5]
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References
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- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ Cui Y, et al. (1995) Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes Dev 9(4):423-36 SGD PMID 7883167
- ↑ 3.0 3.1 He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54 SGD PMID 7883168
- ↑ He F, et al. (1997) Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol Cell Biol 17(3):1580-94 SGD PMID 9032286
- ↑ submitted by Jurgen Wittmann on 2003-04-30
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