YHR077C

From SGD-Wiki
(Redirected from UPF2)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YHR077C
Gene name NMD2
Aliases IFS1, SUA1, SUP111, UPF2
Feature type ORF, Verified
Coordinates Chr VIII:255756..252374
Primary SGDID S000001119


Description of YHR077C: Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance[1][2][3][4]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Interactions

Two Hybrid

Two Hybrid interaction with NAM7
Yeast Two-Hybrid screen with Upf1p as bait identified several interacting proteins [3] [5]





<protect>

References

See Help:References on how to add references

  1. Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
  2. Cui Y, et al. (1995) Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon. Genes Dev 9(4):423-36 SGD PMID 7883167
  3. 3.0 3.1 He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54 SGD PMID 7883168
  4. He F, et al. (1997) Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol Cell Biol 17(3):1580-94 SGD PMID 9032286
  5. submitted by Jurgen Wittmann on 2003-04-30

See Help:Categories on how to add the wiki page for this gene to a Category </protect>