YDR092W

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Systematic name YDR092W
Gene name UBC13
Aliases
Feature type ORF, Verified
Coordinates Chr IV:629876..630605
Primary SGDID S000002499


Description of YDR092W: Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus[1][2][3]




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References

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  1. Brusky J, et al. (2000) UBC13, a DNA-damage-inducible gene, is a member of the error-free postreplication repair pathway in Saccharomyces cerevisiae. Curr Genet 37(3):168-74 SGD PMID 10794173
  2. Hofmann RM and Pickart CM (1999) Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell 96(5):645-53 SGD PMID 10089880
  3. Ulrich HD and Jentsch S (2000) Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J 19(13):3388-97 SGD PMID 10880451

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