YGR186W
(Redirected from TFG1)
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| Systematic name | YGR186W |
| Gene name | TFG1 |
| Aliases | RAP74, SSU71 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:867774..869981 |
| Primary SGDID | S000003418 |
Description of YGR186W: TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74[1][2]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]
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References
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- ↑ Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503 SGD PMID 9618449
- ↑ Sun ZW and Hampsey M (1995) Identification of the gene (SSU71/TFG1) encoding the largest subunit of transcription factor TFIIF as a suppressor of a TFIIB mutation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 92(8):3127-31 SGD PMID 7724527
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-27
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