YNR023W

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Systematic name YNR023W
Gene name SNF12
Aliases SWP73
Feature type ORF, Verified
Coordinates Chr XIV:670418..672118
Primary SGDID S000005306


Description of YNR023W: 73 kDa subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; relocates to the cytosol under hypoxic conditions; deletion mutants are temperature-sensitive[1][2][3][4][5]




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References

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  1. Cairns BR, et al. (1996) Essential role of Swp73p in the function of yeast Swi/Snf complex. Genes Dev 10(17):2131-44 SGD PMID 8804308
  2. Cairns BR, et al. (1996) RSC, an essential, abundant chromatin-remodeling complex. Cell 87(7):1249-60 SGD PMID 8980231
  3. Ghosh Dastidar R, et al. (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2(1):30 SGD PMID 22932476
  4. Miller ME, et al. (1996) Adenovirus E1A specifically blocks SWI/SNF-dependent transcriptional activation. Mol Cell Biol 16(10):5737-43 SGD PMID 8816487
  5. Sudarsanam P and Winston F (2000) The Swi/Snf family nucleosome-remodeling complexes and transcriptional control. Trends Genet 16(8):345-51 SGD PMID 10904263

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