YJL128C

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Systematic name YJL128C
Gene name PBS2
Aliases HOG4, SFS4, SSK4
Feature type ORF, Verified
Coordinates Chr X:180103..178097
Primary SGDID S000003664


Description of YJL128C: MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition[1][2][3]




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References

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  1. Bansal PK, et al. (2001) A PBS2 homologue from Debaryomyces hansenii shows a differential effect on calcofluor and polymyxin B sensitivity in Saccharomyces cerevisiae. Yeast 18(13):1207-16 SGD PMID 11561288
  2. Nyswaner KM, et al. (2008) Chromatin-associated genes protect the yeast genome from ty1 insertional mutagenesis. Genetics 178(1):197-214 SGD PMID 18202368
  3. Van Wuytswinkel O, et al. (2000) Response of Saccharomyces cerevisiae to severe osmotic stress: evidence for a novel activation mechanism of the HOG MAP kinase pathway. Mol Microbiol 37(2):382-97 SGD PMID 10931333

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