YDR308C

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Systematic name YDR308C
Gene name SRB7
Aliases MED21
Feature type ORF, Verified
Coordinates Chr IV:1078449..1078027
Primary SGDID S000002716


Description of YDR308C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p[1][2][3]




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References

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  1. Gromoller A and Lehming N (2000) Srb7p is a physical and physiological target of Tup1p. EMBO J 19(24):6845-52 SGD PMID 11118219
  2. Hengartner CJ, et al. (1995) Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 9(8):897-910 SGD PMID 7774808
  3. Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740

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