YPR101W

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Systematic name YPR101W
Gene name SNT309
Aliases NTC25
Feature type ORF, Verified
Coordinates Chr XVI:730492..731019
Primary SGDID S000006305


Description of YPR101W: Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; interacts physically and genetically with Prp19p[1][2][3][4]




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References

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  1. Chen CH, et al. (2006) Functional links between the Prp19-associated complex, U4/U6 biogenesis, and spliceosome recycling. RNA 12(5):765-74 SGD PMID 16540691
  2. Chen HR, et al. (1998) Snt309p, a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultaneously with or immediately after dissociation of U4 in the same manner as Prp19p. Mol Cell Biol 18(4):2196-204 SGD PMID 9528791
  3. Chen HR, et al. (1999) Snt309p modulates interactions of Prp19p with its associated components to stabilize the Prp19p-associated complex essential for pre-mRNA splicing. Proc Natl Acad Sci U S A 96(10):5406-11 SGD PMID 10318896
  4. Ohi MD and Gould KL (2002) Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. RNA 8(6):798-815 SGD PMID 12088152

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