YGR195W
(Redirected from SKI6)
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| Systematic name | YGR195W |
| Gene name | SKI6 |
| Aliases | ECM20, RRP41 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:888882..889622 |
| Primary SGDID | S000003427 |
Description of YGR195W: Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4)[1][2][3][4][5][6]
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References
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- ↑ Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 SGD PMID 10465791
- ↑ Benard L, et al. (1998) Ski6p is a homolog of RNA-processing enzymes that affects translation of non-poly(A) mRNAs and 60S ribosomal subunit biogenesis. Mol Cell Biol 18(5):2688-96 SGD PMID 9566888
- ↑ Dziembowski A, et al. (2007) A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nat Struct Mol Biol 14(1):15-22 SGD PMID 17173052
- ↑ Liu Q, et al. (2006) Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell 127(6):1223-37 SGD PMID 17174896
- ↑ Mitchell P, et al. (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell 91(4):457-66 SGD PMID 9390555
- ↑ Synowsky SA, et al. (2006) Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex. Mol Cell Proteomics 5(9):1581-92 SGD PMID 16829593
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