YKR101W
(Redirected from SIR1)
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| Systematic name | YKR101W |
| Gene name | SIR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:640540..642504 |
| Primary SGDID | S000001809 |
Description of YKR101W: Protein involved in repression of transcription at the silent mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin[1][2][3]
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References
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- ↑ Bose ME, et al. (2004) The origin recognition complex and Sir4 protein recruit Sir1p to yeast silent chromatin through independent interactions requiring a common Sir1p domain. Mol Cell Biol 24(2):774-86 SGD PMID 14701749
- ↑ Rine J and Herskowitz I (1987) Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116(1):9-22 SGD PMID 3297920
- ↑ Sharp JA, et al. (2003) The budding yeast silencing protein Sir1 is a functional component of centromeric chromatin. Genes Dev 17(19):2356-61 SGD PMID 12975325
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