YDR181C

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Systematic name YDR181C
Gene name SAS4
Aliases
Feature type ORF, Verified
Coordinates Chr IV:827355..825910
Primary SGDID S000002589


Description of YDR181C: Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; required for the HAT activity of Sas2p[1][2]




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References

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  1. Shia WJ, et al. (2005) Characterization of the yeast trimeric-SAS acetyltransferase complex. J Biol Chem 280(12):11987-94 SGD PMID 15659401
  2. Sutton A, et al. (2003) Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex. J Biol Chem 278(19):16887-92 SGD PMID 12626510

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