YOR048C
(Redirected from S000005574)
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| Systematic name | YOR048C |
| Gene name | RAT1 |
| Aliases | HKE1, TAP1, XRN2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:421650..418630 |
| Primary SGDID | S000005574 |
Description of YOR048C: Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism, including rRNA and snRNA processing as well as poly (A+) dependent and independent mRNA transcription termination[1][2][3][4]
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References
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- ↑ Amberg DC, et al. (1992) Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA. Genes Dev 6(7):1173-89 SGD PMID 1628825
- ↑ Ghazal G, et al. (2009) Yeast RNase III triggers polyadenylation-independent transcription termination. Mol Cell 36(1):99-109 SGD PMID 19818713
- ↑ Johnson AW (1997) Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively. Mol Cell Biol 17(10):6122-30 SGD PMID 9315672
- ↑ Kim M, et al. (2004) The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II. Nature 432(7016):517-22 SGD PMID 15565157
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