YOL115W
(Redirected from S000005475)
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| Systematic name | YOL115W |
| Gene name | PAP2 |
| Aliases | TRF4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:101475..103229 |
| Primary SGDID | S000005475 |
Description of YOL115W: Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Trf5p[1][2][3][4]
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References
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- ↑ Gellon L, et al. (2008) Intrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. DNA Repair (Amst) 7(2):187-98 SGD PMID 17983848
- ↑ LaCava J, et al. (2005) RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell 121(5):713-24 SGD PMID 15935758
- ↑ Vanacova S, et al. (2005) A new yeast poly(A) polymerase complex involved in RNA quality control. PLoS Biol 3(6):e189 SGD PMID 15828860
- ↑ Wyers F, et al. (2005) Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell 121(5):725-37 SGD PMID 15935759
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